Sir, Angiodermatitis is a common disorder with a clinical and morphological resemblance to Kaposi's sarcoma. In 1965, Mali et al. described the condition ``acro-angidermatitis'' in 18 patients with chronic venous insu¤ciency (1). Other names for this disorder are Stewart-Bluefard syndrome, angiodermatitis, congenital dysplastic angiography, Kaposi-like arteriovenous malformation (AVM) and pseud...

As obligate intracellular parasites, viruses exploit diverse cellular signaling machineries, including the mitogen-activated protein-kinase pathway, during their infections. We have demonstrated previously that the open reading frame 45 (ORF45) of Kaposi sarcoma-associated herpesvirus interacts with p90 ribosomal S6 kinases (RSKs) and strongly stimulates their kinase activities ( Kuang, E., Tan...

Kaposi sarcoma (KS) is a soft-tissue malignancy arising from the proliferation of spindle cells with vascular endothelial cell origin. The disease most frequently affects mucocutaneous tissues as well as the visceral aerodigestive tract. Lesions can arise anywhere along the digestive tract from the oral cavity to the perianal region. Human herpesvirus 8 (HHV-8) is a crucial factor in disease pa...

HHV-8: human herpesvirus-8 KS: Kaposi sarcoma MSM: men who have sex with men INTRODUCTION Kaposi sarcoma (KS) is an indolent angioproliferative tumor thought to be dependent on viral replication, immune modulation, and inflammatory cytokines produced by infected endothelial and immune cells. Human herpesvirus-8 (HHV-8) is thought to cause KS and is documented in more than 95% of patients with K...

OBJECTIVE To report a case of a schwannoma of nasopalpebral location, occurring in a human immunodeficiency virus (HIV)-positive patient. CLINICAL PRESENTATION AND INTERVENTION A 55-year-old man presented with a nasopalpebral painless tumefaction, pneumopathy and HIV-related immunodepression after stopping combination antiretroviral therapy. Magnetic resonance imaging showed subcutaneous mass...

Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. This form of Kaposi´s sarcoma is rare. It occurs more in younger patients than in the classic form, is lim...