El sarcoma de Kaposi (SK) es un tumor angioproliferativo asociado al virus del herpes 8. Según la forma clínica que desarrolle y el estado inmunitario paciente, puede manifestarse como una lesión cutánea única o ser enfermedad diseminada.
 tratamiento dependerá clínica, extensión las lesiones condiciones médicas preexistentes. Esto irá desde observación los tratamientos tópicos e intralesi...

Intra-host tumor virus variants may influence the pathogenesis and treatment responses of some virally-associated cancers. However, intra-host variability Kaposi sarcoma-associated herpesvirus (KSHV), etiologic agent sarcoma (KS), has to date been explored with sequencing technologies that possibly introduce more errors than which occurs in viral population, these studies have only studied vari...

El KSHV / HHV-8 está asociado con el sarcoma de Kaposi (KS), así como trastornos linfoproliferativos, principalmente en pacientes infección por VIH SIDA. Aunque la asociación entre linfomas y se ha descrito, presencia simultánea las 2 entidades dentro del mismo órgano es rara asocia Presentamos un caso aparición linfoma angioinmunoblástico linfonodo, además concurrente herpes virus (KSHV) Epste...

  Background and Objectives:  The molecular genetic of the human herpes virus 8 (HHV8) has now been characterized the pathogenesis of kaposi sarcoma (KS). This study attempted to determine the rate of HHU-8 infection in KS in an Iraniann cross sectional study. Method & material: In this cross-sectional study, we used paraffin-embedded specimens of 54 clinically well-characterized kaposi sarcom...

Kaposi sarcoma (KS) was first described by Kaposi in 1872. There are four clinical types of the disease: classic, endemic, epidemic and iatrogenic [1]. Iatrogenic KS develops in patients taking immunosuppressive treatment. Bluish-reddish coloration is seen in 84% of KS lesions in dermatoscopy. Rainbow pattern and scaly surface are other dermatoscopic features of KS (36% and 15%, respectively) [...

As obligate intracellular parasites, viruses exploit diverse cellular signaling machineries, including the mitogen-activated protein-kinase pathway, during their infections. We have demonstrated previously that the open reading frame 45 (ORF45) of Kaposi sarcoma-associated herpesvirus interacts with p90 ribosomal S6 kinases (RSKs) and strongly stimulates their kinase activities ( Kuang, E., Tan...

Kaposi sarcoma (KS) is a soft-tissue malignancy arising from the proliferation of spindle cells with vascular endothelial cell origin. The disease most frequently affects mucocutaneous tissues as well as the visceral aerodigestive tract. Lesions can arise anywhere along the digestive tract from the oral cavity to the perianal region. Human herpesvirus 8 (HHV-8) is a crucial factor in disease pa...

HHV-8: human herpesvirus-8 KS: Kaposi sarcoma MSM: men who have sex with men INTRODUCTION Kaposi sarcoma (KS) is an indolent angioproliferative tumor thought to be dependent on viral replication, immune modulation, and inflammatory cytokines produced by infected endothelial and immune cells. Human herpesvirus-8 (HHV-8) is thought to cause KS and is documented in more than 95% of patients with K...