● Rheumatoid arthritis (RA) and Juvenile RA (JRA) joints; less commonly lung, skin ● Lupus (Systemic Lupus Erythematosus) skin, joints, kidneys, heart, brain, red blood cells, other ● Scleroderma skin, intestine, less commonly lung ● Sjogren's syndrome salivary glands, tear glands, joints ● Goodpasture's syndrome lungs, kidneys ● Wegener's granulomatosis blood vessels, sinuses, lungs, kidneys ●...

Juvenile rheumatoid arthritis (JRA) has a complex, poorly characterized pathophysiology. Modeling of transcriptosome behavior in pathologic specimens using microarrays allows molecular dissection of complex autoimmune diseases. However, conventional analyses rely on identifying statistically significant differences in gene expression distributions between patients and controls. Since the princi...

By using a sandwich ELISA, soluble human IL-6 receptor (sIL-6 R) levels were measured in the sera of 20 healthy children and of 25 patients with systemic juvenile rheumatoid arthritis (JRA). In patients with systemic JRA, serum sIL-6 R levels (114.6 +/- 37.7 ng/ml) were significantly lower (P < 0.01) than those of healthy children (161.2 +/- 45.5 ng/ml). Serum sIL-6 R levels were negatively cor...

● Rheumatoid arthritis (RA) and Juvenile RA (JRA) joints; less commonly lung, skin ● Lupus (Systemic Lupus Erythematosus) skin, joints, kidneys, heart, brain, red blood cells, other ● Scleroderma skin, intestine, less commonly lung ● Sjogren's syndrome salivary glands, tear glands, joints ● Goodpasture's syndrome lungs, kidneys ● Wegener's granulomatosis blood vessels, sinuses, lungs, kidneys ●...

● Rheumatoid arthritis (RA) and Juvenile RA (JRA) joints; less commonly lung, skin ● Lupus (Systemic Lupus Erythematosus) skin, joints, kidneys, heart, brain, red blood cells, other ● Scleroderma skin, intestine, less commonly lung ● Sjogren's syndrome salivary glands, tear glands, joints ● Goodpasture's syndrome lungs, kidneys ● Wegener's granulomatosis blood vessels, sinuses, lungs, kidneys ●...

Evidence has been sought for a genetically determined predisposition among children with juvenile rheumatoid arthritis (JRA) who are also at particular risk for the development of inflammatory eye disease.45 unrelated Caucasian patients (41 female) with early-onset pauciarticular JRA were human leukocyte antigen (HLA) types. 28 of the study group were found to be HLA-DRw5 compared with 16 of 84...

Water table elevation is a key feature for identifying the groundwater behaviour. Accordingly, appropriate measurements—in terms of both frequency and spatial distribution—play crucial role capturing aquifer response to recharge withdrawals. However, numerical models simulating main features behaviour water may help management, as an additional tool. In this article, soil moisture data from thr...