Juvenile Justice-Translating Research Interventions for Adolescents in the Legal System (JJ-TRIALS; a cooperative implementation science initiative launched by NIDA in July 2013) seeks to reduce unmet substance use disorder (SUD) needs by assisting JJ agencies in their efforts to implement best practices and improve SUD service utilization along a behavioral health cascade (screening, assessmen...

S290 (2000). 41 Goronzy JJ, Fujii H, Weyand CM. Telomeres, immune aging and autoimmunity. Exp. Gerontol. 41(3), 246–251 (2006). n„ Presents important findings related to aging and how age influences autoimmunity. 42 Schonland SO, Lopez C, Widmann T et al. Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc. Natl A...

1. Hepatic bilirubin UDP-glucuronosyl transferase activity in heterozygous Gunn rats (Jj) was only two-thirds of that in the parent Wistar rats (JJ). The former excreted only 30% of their bilirubin conjugates into bile as diglucuronide in contrast to 48% in the Wistar rats. As similar changes have been observed in Gilbert's syndrome, heterozygous Gunn rats can be used as a model for this disord...

Kernicterus is known to produce damage to the auditory system and the basal ganglia in humans. Although the Gunn rat model of kernicterus has been extensively used to characterize the auditory features, this model has not been similarly utilized to systematically investigate the movement disorder. In the present study, spontaneously jaundiced (jj) 16 day old Gunn rat pups were treated with sulf...

Paenibacillus sp. (formerly Bacillus macerans) strain JJ-1b is able to grow on 4-hydroxybenzoate (4HB) as a sole source of carbon and energy and is known to degrade 4HB via the protocatechuate (PCA) 2,3-cleavage pathway. However, none of the genes involved in this pathway have been identified. In this study, we identified and characterized the JJ-1b genes for the 4HB catabolic pathway via the P...

We consider two semi-online scheduling problems on a single batch (processing) machine with jobs’ nondecreasing processing times and jobs’ nonincreasing processing times, respectively. Our objective is to minimize the makespan. A batch processing machine can handle up to B jobs simultaneously. We study an unbounded model where B = ∞. The jobs that are processed together construct a batch, and a...

Epitaxial Al-InAs heterostructures appear as a promising materials platform for exploring mesoscopic and topological superconductivity. A unique property of Josephson junction field effect transistors (JJ-FETs) fabricated on these is the ability to tune supercurrent using metallic gate. Here, we report fabrication measurement gate-tunable JJ-FETs in which gate dielectric contact with InAs produ...

Superconducting weak link (WL), acting as a Josephson junction (JJ), is one of the widely used elements in superconductor science and quantum circuits. A hysteretic JJ with robust switching between its superconducting resistive state an excellent candidate for single-photon detection. However, ubiquitous fluctuations strongly influence stability states and, thus, transition from to other. Here,...

A prominent source of complexity in the verification of ad hoc network (AHN) protocols is the fact that the number of network topologies grows exponentially with the square of the number of nodes. To combat this instance explosion problem, we present a query-based verification framework for AHN protocols that utilizes symbolic reachability analysis. Specifically we consider AHN nodes of the for...

OBJECTIVE To examine the prevalence of substance use disorders (SUDs) among adolescents who received services in one or more of the following public sectors of care: alcohol and drug (AD), juvenile justice (JJ), mental health (MH), public school-based services for youths with serious emotional disturbance (SED), and child welfare (CW), in relation to age, gender, and service sector affiliation....