Lifestyle modifications such as diet change and exercise therapy are recommended as first-line therapy for risk factors for atherosclerotic cardiovascular diseases (ASCVD). Ancel Keys et al., in their landmark epidemiological study, the Seven Countries Study, which started in 1958 1) , reported that a high serum cholesterol level is a risk factor for coronary artery diseases (CAD) and that a hi...

potent hypotensive activity prepared by the Hantzsch reaction. J Pharm Pharmacol 24: 917-918, 1972 11. Fielden R, Owen DAA, Taylor EM: Hypotensive and vasodilator actions of SK&F 24260, a new dihydropyridine derivative. Br J Pharmacol 52: 323-332, 1974 12. Imai Y, Himori N, Taira N: Cardiohemodynamic effects of SK&F 24260, D 600, diltiazem, dilazep and trimetazidine in the dog. Jap Heart J 18: ...

the international intellectual landscape. For example , Figure 1 shows some results from a biblio-metric study that my colleagues and I conducted at the University of Arizona's AI Lab. 1 The study was based on academic nanotechnology papers published in the Thomson Science Citation In-dex's (SCI) Web of Sciences and the UK were the major countries publishing nanotechnology research. After 1991,...

potent hypotensive activity prepared by the Hantzsch reaction. J Pharm Pharmacol 24: 917-918, 1972 11. Fielden R, Owen DAA, Taylor EM: Hypotensive and vasodilator actions of SK&F 24260, a new dihydropyridine derivative. Br J Pharmacol 52: 323-332, 1974 12. Imai Y, Himori N, Taira N: Cardiohemodynamic effects of SK&F 24260, D 600, diltiazem, dilazep and trimetazidine in the dog. Jap Heart J 18: ...

Editor's Note: These short, critical reviews of recent papers in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to summarize the important findings of the paper and provide additional insight and commentary. For more information on the format and purpose of the Journal Club, please see Review of Nagarajan et al. Mammalian dopaminergic neurons of the ...

THE SUBDIVISION of skeletal muscle into distinct fiber types based on myosin heavy chain (MHC) isoform expression [I, IIa, and IIx in humans; I, IIa, IIx, and IIb in rodents (9)], has proven to be a practical and lasting working concept not only in studies of contractile properties but in the general study of muscle physiology. Hence, in the past 30–40 years, a wealth of rodent data, interspers...

(98) Eleiotis DC. (1825) [Angiosp.: Legum.] Eleotis Ver.-Lib. & R.D. Stone (2020) Melastomat.] The genus was first established by the Swiss botanist Augustin Pyramus de Candolle (Prodr. 2: 348. Nov 1825) with monophylla (l.c.) (the epithet taken from illegitimate Glycine monophyllos Burm. f., Fl. Ind.: 161. 1768, non L. 1767) and E. sororia (L.) (≡ Hedysarium sororium L., Mant. Pl. Alt.: 270. 1...

It is now known that prenatal ethanol (EtOH) exposure is associated with impaired glucose tolerance and insulin resistance in the rat offspring, but the underlying mechanism(s) is not known. To test the hypothesis that in vivo insulin signaling through PI 3-kinase is reduced in skeletal muscle of adult rat offspring exposed to EtOH in utero, we gave insulin intravenously to these rats and probe...

Background Cross sectional research shows that nearly half of the individuals with osteoarthritis (OA) experience fatigue and over one third severe (1). However, few studies have addressed unpredictable fluctuating course in OA including occurrence overwhelming as evidenced from qualitative (2). In-depth understanding its determinants may inform clinical decision making treatment. Objectives To...

A growing field of literature is studying how usability impacts security [4]. One class of security software is anonymizing networks— overlay networks on the Internet that provide privacy by letting users transact (for example, fetch a web page or send an email) without revealing their communication partners. In this position paper we focus on the network effects of usability on privacy and sec...