Additionally, there is an increasing need to maintain easy access to historical information for business or regulatory requirements. For example, a company may need to protect its interests by retrieving historical financial transactions to satisfy customer inquiries and resolve claims. In other cases, corporate policy or government regulations dictate that data must remain accessible for years...

A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.

Access control mechanisms are needed in almost every system nowadays to control what kind of access each user has to which resources and when. On the one hand access control systems need to be flexible to allow the definition of the access rules that are actually needed. But they must also be easy to administrate to prevent rules from being in place without the administrator realizing it. This ...

Flavivirus reveals its access code Fritz et al. have identifi ed an amino acid switch that fl aviviruses fl ip to gain access to cells. Flaviviruses such as tick-borne encephalitis virus (TBEV), yellow fever, and dengue are dangerous human pathogens. These membrane-encircled viruses enter cells by being gobbled up into endosomes and fusing their membrane with that of the endosome. Fusion is tri...

The story told in this lecture starts with an innocuous little geometry problem (one that Erdős would have liked), posed in a September 2006 blog entry by R. Nandakumar, an engineer from Calcutta, India: “Can you cut every polygon into a prescribed number of convex pieces that have equal area and equal perimeter?” This little problem is a “sparrow”, tantalizing, not as easy as one could perhaps...

Due to its easy and user-friendly features, the world-wide web (WWW) has become one of the most popular tools in the internet. It allows fast and easy access to a huge amount of information all over the world whilst sparing the user the effort to care about the location of the information he is looking for; a click on the appropriate hyperlink automatically directs the user to the correct place...

A compact minicryostat has been well adapted on the hard x-ray microprobe ID22 of the European Synchrotron Radiation Facility. For variable low-temperature investigations, its special technical design provides precise scanning microscopy and allows easy access for multiple detection modes. Based on x-ray excited optical luminescence technique on the micrometer scale, details of the equipment, i...