Exercise is a potent stimulus to activate the sympathetic nervous system. Previous work suggests that metabolite-sensitive muscle afferents are activated near the point of fatigue, and, when activated, they determine the muscle sympathetic nerve activity (MSNA) response to isometric forearm exercise. Yet, studies using a more prolonged rhythmic exercise paradigm suggest that the sympathetic ner...

Muscle power is more functionally relevant than static muscle strength, particularly with aging. However, the effect of age on power derived from isotonic contractions has been studied sparingly, and it has not been studied at all in subjects >75 yr of age. Thus the purpose was to investigate the magnitude and causes of age-related losses in isotonic power among 13 young (26 yr), 13 old (65 yr)...

Aims: Active and progressive resistance training has a key role in functional recovery and quality of life in patients with MS. Therefore, this study aimed to investigate the effects of isotonic and isometric exercises on balance and ability in patients with MS. Materials & Methods: In this randomized clinical trial, 60 patients with MS admitted to MS Special Diseases Center in Yasuj during 20...

Abstract Isotonic distributional regression (IDR) is a powerful non-parametric technique for the estimation of conditional distributions under order restrictions. In nutshell, IDR learns that are calibrated, and simultaneously optimal relative to comprehensive classes relevant loss functions, subject isotonicity constraints in terms partial on covariate space. Non-parametric isotonic quantile b...

BURNS, JOHN W., AND JAMES W. COVELL. Myocardial oxygen consumption during isotonic and isovolumic contractions in the intact heart. Am. J. Physiol. 223(6): 1491-1497. 1972.-There is now substantial evidence that the oxygen cost of performing external cardiac work is less than that associated with the development of active tension. However, because of the complex geometry of the contracting hear...

OBJECTIVE To assess the reliability of knee extensor and flexor muscle strength measurements in persons with late effects of polio. DESIGN A test-retest reliability study. SUBJECTS Thirty men and women (mean age 63 (standard deviation 6.4) years) with verified late effects of polio. METHODS Knee extensor and flexor muscle strength in both lower limbs were measured twice 7 days apart using...