Taxonomic changes have frequently occurred in the anuran genus Pseudopaludicola as a consequence of high morphological similarity among its species. The present work reports karyotypic analysis of three Pseudopaludicola species sampled in their type locality and four Pseudopaludicola populations from distinct localities, aiming at contributing to the systematics of this genus. Chromosomes were ...

—Nine-year old artifi cially regenerated red oak (Quercus rubra L.), white oak (Q. alba L.), and shortleaf pine (Pinus echinata Mill.) trees were excavated from plot borders of a U.S. Forest Service long-term soil productivity study in the Carr Creek State Forest near Ellington, MO, to quantify treatment eff ects on aboveand belowground tree biomass. Th e study consists of factorial combination...

Microalgae culture is a potential source of biodiesel and one of the best alternatives as raw material for biodiesel production. The first objective of this work is the pilot plant design for microalgae culture of high oil content species. The design was inspired by raceway large-scale culture. Although this kind of culture is usually in outdoor ponds, the pilot plant is an indoor raceway pond,...

It has been widely assumed that fresh oocytes are required for the establishment of embryonic stem cells (ES cells) via somatic cell nuclear transfer (SCNT). Such cell lines are referred to as ‘NT-ES cells’ [1]. This presumed requirement, however, gives rise to fundamental ethical concerns surrounding its potential application to human cells, as fresh oocytes must be obtained from a healthy fem...

Atypical femur fractures (AFF) caused by long term Bisphosphonate use are associated with high rates of delayed healing and non-union, posing a significant challenge in the management these patients. We describe case 64-year-old female osteopenia on therapy for 15 years who sustained displaced left AFF following fall from standing height. She reported 6-month history antecedent groin pain. Radi...

Rare diseases aff ect a limited number of individuals (defi ned as no more than one in 2000 individuals in the European Union and no more than about one in 1250 in the USA), but the number of disorders that fi t this defi nition is very large (>5000 according to WHO). Therefore, the number of patients aff ected by a rare disease could be about 30 million in Europe and 25 million in North Americ...

A diagnosis of HIV aff ects every aspect of a person’s life. Simple awareness of the disease, as well as progression of symptoms, can precipitate new, or exacerbate existing, problems with mental health and substance abuse. In turn, such problems increase an individual’s need for health care services and interfere with his or her ability to comply with complex treatment regimens. What’s more, p...

BACKGROUND Bisphosphonates (BPs) are the most commonly used anti-osteoporotic drugs, which have been proven to reduce the risk of osteoporotic fractures. However, use of BPs, particularly for long periods of time, is associated with an increased risk of atypical femoral fracture (AFF). Healing of BP-associated AFF is usually delayed because of suppressed bone turnover. Teriparatide (TPTD), a re...

For human vaccines to be available on a global scale, complex production methods, meticulous quality control, and reliable distribution channels are needed to ensure that the products are potent and eff ective at the point of use. The technologies used to manufacture diff erent types of vaccines can strongly aff ect vaccine cost, ease of industrial scale-up, stability, and, ultimately, worldwid...