Background & Aims: Irritable bowel syndrome (IBS) is the most prevalent gastrointestinal functional disorder, characterized by non-specific symptoms such as abdominal pain and discomfort, altered bowel habit, and bloating. Its prevalence varies between 3.5% and 30% in the world. This study was conducted in order to determine the prevalence of IBS in the adult population of Kerman, Iran, which i...

Abstract Evidence suggests that sigmoid-colonic motility is increased in patients with irritable bowel syndrome (IBS). 5-Hydroxytryptamine (5-HT) plays a role in the control of motility, but its involvement in the dysmotility seen in IBS remains unclear. To investigate the relationship between platelet depleted plasma 5-HT (PDP 5-HT) concentration and sigmoid-colonic motility in patients with I...

Irritable bowel syndrome is a disorder diagnosed on symptom-based criteria without inclusion of any objective parameter measurable by known diagnostic methods. Heterogeneity of the disorder and overlapping with more serious organic diseases increase uncertainty for the physician's work and increase the cost of confirming the diagnosis. This paper is an attempt to summarize the efforts to find a...

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with an estimated prevalence of 10-20%. Current understanding of the pathophysiology of IBS is incomplete due to the lack of a clearly identified pathological abnormality and due to the lack of reliable biomarkers. Possible mechanisms believed to contribute to IBS development and IBS like symptoms include physical stressors, s...

background: the rome ii and iii diagnostic criteria for dyssynergic defecation recommended the exclusion of irritable bowel syndrome (ibs). this study determined the effect of biofeedback therapy on dyssynergic constipation in patients with or without  irritable bowel syndrome. materials and methods: this study was a non-randomized, single blinded, semi experimental study. dyssynergic defecatio...

Irritable bowel syndrome (IBS) is the most common functional bowel disorder diagnosed by primary care physicians and gastroenterologists. Estimation of the exact prevalence of IBS is complicated, because up to 70% of persons with symptoms of IBS do not seek medical treatment. The ratio of female-to-male sufferers is approximately 2:1. IBS affects up to 1 in 5 Americans and is second only to the...

Irritable bowel syndrome (IBS) is one of the most common chronic gastrointestinal disorders, yet its pathophysiology is incompletely understood and pharmacological treatments remain unsatisfactory. Current therapeutic choices include a range of drugs aimed at normalising bowel habits, reducing pain or treating comorbid psychological symptoms. However, this individual symptom-targeted approach r...

There is limited data on the role of intestinal parasites in irritable bowel syndrome (IBS) in South America. We evaluated the association between intestinal parasitism and IBS status in Peru. Intestinal parasites were detected in 43% of the IBS cases and in 51% of the controls (P = 0.4). After excluding those infected by any parasite, the IBS prevalence remained high (22%; P = 0.7). No statist...

Irritable bowel syndrome (IBS) is one of the most commonly encountered functional gastrointestinal disorders in the elderly. IBS is characterized by abdominal pain and altered bowel habits in the absence of specific organic pathology. The diagnosis of IBS usually depends primarily on established clinical criteria. Currently, Rome III criteria are the criteria of choice for defining IBS. However...