Irritable bowel syndrome affects 10 to 15 percent of the U.S. population to some degree. This condition is defined as abdominal pain and discomfort with altered bowel habits in the absence of any other mechanical, inflammatory, or biochemical explanation for these symptoms. Irritable bowel syndrome is more likely to affect women than men and is most common in patients 30 to 50 years of age. Sym...

BACKGROUND Post-infectious irritable bowel syndrome is associated with increased serotonin-containing enterochromaffin cells and lymphocytes in rectal biopsies. Animal studies have suggested that steroids reduce the lymphocyte response and suppress some of the post-infectious changes in neuromuscular function. AIM To evaluate whether steroids reduce the number of enterochromaffin cells and im...

Irritable bowel syndrome is defined as abdominal discomfort or pain associated with altered bowel habits for at least three days per month in the previous three months, with the absence of organic disease. In North America, the prevalence of irritable bowel syndrome is 5 to 10 percent with peak prevalence from 20 to 39 years of age. Abdominal pain is the most common symptom and often is describ...

of patient presentations at gastrointestinal clinics, and up to 50% or more of patients presenting with abdominal symptoms have no organic abnormality detected. The most common functional gastrointestinal conditions in Canada are irritable bowel syndrome (IBS), and functional dyspepsia or nonulcer dyspepsia (NUD). Other functional disorders may affect specific regions of the alimentary tract, s...

background : irritable bowel syndrome (ibs) is a disorder of the gastrointestinal system that presents with special gastrointestinal signs and lack of an organic etiology. quality of life (qol) is one of the most important outcomes of ibs. several psychological factors are mentioned as effective in determining qol in ibs patients. the goal of this study is to determined the relationship between...

background: irritable bowel syndrome (ibs) is one of the most common functional gastrointestinal disorders. a signi_cant number of ibs patients have extra-intestinal symptoms (eis), but the etiology of co-morbidity of ibs with these symptoms is unclear. the aim of this study was to evaluate the relationship of eis with psychological symptoms in ibs patients. â  materials and methods: this multi...

Irritable bowel syndrome (IBS)-a complex, multifaceted condition, broadly characterized by abdominal pain/discomfort associated with altered bowel habits-is among the most prevalent gastrointestinal motility disorders and is one the commonest conditions seen by gastroenterologists in their daily practice.(1), In clinical practice, a positive diagnosis of IBS is usually made by symptom criteria ...

Background It has been proposed that allergy may be considered as one of the common associated conditions, like irritable bowel syndrome or migraine in fibromyalgia. Fibromyalgia is a clinical entity classified by the presence of chronic widespread pain in at least 11 of the 18 specified tender points and associated with symptoms like fatigue, irritable bowel, sleep disorder, chronic headaches,...

Prokinetic drugs are being used with increasing frequency in the treatment of functional gastrointestinal disorders including functional dyspepsia (FD) and constipation-predominant Irritable Bowel Syndrome (IBS-C). Mosapride is a gastro-prokinetic agent that acts as a selective 5-HT4 agonist thereby accelerating gastric emptying. It has been used for the treatment of irritable bowel syndrome (I...

BACKGROUND Untreated celiac disease has traditionally been linked to a greater risk for small intestinal bacterial overgrowth, but the existing evidence is inconclusive. AIMS To compare the prevalence of small intestinal bacterial overgrowth in subjects with celiac disease compared with control subjects and patients with irritable bowel syndrome. MATERIAL AND METHODS The study included 15 u...