Iron limitation is one major constraint of microbial life, and a plethora of microbes use siderophores for high affinity iron acquisition. Because specific enzymes for reductive iron release in gram-positives are not known, we searched Firmicute genomes and found a novel association pattern of putative ferric siderophore reductases and uptake genes. The reductase from the schizokinen-producing ...

Iron is an essential element for all organisms, and microorganisms produce small molecule iron-chelators, siderophores, to efficiently acquire Fe(III). Gram-positive bacteria possess lipoprotein siderophore-binding proteins (SBPs) on the membrane. Some of the SBPs bind both apo-siderophores (iron-free) and Fe-siderophore (iron-chelated) and only import Fe-siderophores. When the SBP initially bi...

Polynuclear Iron(II) and Iron(III) derivatives of 1-Aminoethylidenediphosphonic acid (AEDP, H4L 1), Alpha-Amino benzylidene diphosphonic acid (ABDP, H4L 2), 1-Amino-2-carboxyethane-1,1diphosphonic acid (ACEDP, H5L 3), 1,3 Diaminopropane-1,1,3,3-tetraphosphonic acid (DAPTP, H8L 4), Diethylene triamine –N,N,N’,N’,N’’N”-penta ( methylene phosphonic ) acid (DETAPMPO, H10L 5),and Diethylene triamine...

The photochemical autoxidation of aqueous, acidic sulfur(IV) solutions was studied in the absence and presence of iron(II) by a newly introduced technique using a diode-array spectrophotometer, in which the same light source is used to drive and detect the reaction. Based on detailed kinetic and stoichiometric data sets, a non-chain mechanism is proposed for the autoxidation of sulfur(IV). In t...

During deposition of Precambrian iron formation, the combined sedimentation of ferrihydrite and phytoplankton biomass should have facilitated Fe(III) reduction during diagenesis. However, the only evidence for this reaction in iron formations is the iron and carbon isotope values preserved in the authigenic ferrous iron-containing minerals. Here we show experimentally that spheroidal siderite, ...

We used the muscle creatine kinase (MCK) conditional frataxin knockout mouse to elucidate how frataxin deficiency alters iron metabolism. This is of significance because frataxin deficiency leads to Friedreich's ataxia, a disease marked by neurologic and cardiologic degeneration. Using cardiac tissues, we demonstrate that frataxin deficiency leads to down-regulation of key molecules involved in...

Iron(II) and iron(III) salts catalyze the oxidative alpha-phosphonation of N,N-dimethylanilines with dialkyl H-phosphonates in the presence of tert-butylhydroperoxide.

The data on the coordination and structure of iron(II) and iron(III) anthranilates in the solid state and in aqueous medium are presented and discussed, as studied using Mössbauer (for solid products and frozen solutions) and FTIR spectroscopy (for solid samples). Whereas, in slightly acidic nitrate solutions under aerobic conditions ferric ions can still be gradually reduced by anthranilic (o-...

Reduction of Fe(III)EDTA by excised roots of soybean seedlings (Glycine max L.) is stimulated by l-malate in the bathing solution. Reduction occurs much more rapidly with roots of seedlings grown in the absence of iron than with roots of seedlings grown with iron. Cell-wall preparations from these roots catalyze reduction of Fe(III)EDTA by NADH. They also contain NAD(+)-dependent l-malate dehyd...

Polyvinyl alcohol/ glycerin- magnetic iron oxide nanoparticles (PVAGLPs) have been synthesized successfully by hydrothermal method. The as-prepared samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectra (FTIR). The adsorbed activities of the polyvinyl alcohol/ glycerin- magnetic iron oxide nano particles (PVAGLPs) were ca...