OBJECTIVES To assess and compare efficacy of two micronutrient sprinkle supplementation on growth, anemia, and iron deficiency in Cambodian infants. METHODS A total of 204 infants aged 6 months and living in Kompong Chhnang Province, Cambodia were randomly assigned to receive daily supplements of either iron (12.5 mg) plus folic acid (150 mug) plus zinc (5 mg) (MMN, n = 68), or iron (12.5 mg)...

It has been shown that the incidence of megaloblastic anaemia in a group of 463 randomly selected pregnant women receiving iron was 12 times as high as in a control group of 235 pregnant women receiving iron and folic acid. The incidence of all types of anaemia in the women receiving iron alone was more than three times the incidence in those having iron and folic acid. Some women who were not ...

A 49-year-old Irishman presented as an emergency with watery diarrhoea and a leuco-erythroblastic anaemia. Investigations showed that he had coeliac disease but no evidence of bone marrow infiltration. His leuco-erythroblastic picture disappeared on treatment with iron and folic acid.

This paper reports on the methods and characteristics of 12 studies from developing countries included in a meta-analysis of the impact of antenatal supplements of multiple micronutrients compared with iron-folic acid on micronutrient status, maternal nutritional status, birth outcomes, and neonatal survival.

INTRODUCTION Anaemia can compromise muscle and organ function. Related iron and vitamin body stores have seldom been assessed in patients with peripheral arterial disease. REPORT We retrospectively analysed basal prevalence of anaemia, iron, B(12)-vitamin and folic acid deficits in 420 patients with claudication and 204 patients with critical limb ischaemia (CLI). The prevalence of the evalua...

Anemia in pregnancy is usually a result of hemodilution and iron/folic acid deficiency. Pure red cell aplasia (PRCA) has rarely been described during pregnancy with only case reports available in English literature. The clinician should be able to distinguish it from aplastic anemia and since, spontaneous recovery can be expected following delivery, neither corticosteroids nor termination of pr...

objective: an association between high homocysteine levels and proteinuria in diabetic nephropathy has been shown. on the other hand, supplementation with folic acid lowers homocysteine concentration. we have studied the effects of folic acid supplementation on proteinuria in type 2 diabetic patients with overt proteinuria. materials and methods: forty five (29 men and 16 women) type 2 diabetic...

In a study of 40 children with kwashiorkor, serum albumin, transferrin, and immunoglobulin levels were measured. Treatment included chloroquine, pyrimethamine, multivitamins, folic acid, iron compounds, and a high-protein diet. After two weeks the mean serum transferrin values in the children who survived and those who died were 1.30 mg./ml. and 0.33 mg./ml., respectively. Many of the children ...

Folic-acid deficiency may arise in conditions which produce an increased demand for the vitamin. Diseases in this category include acute leukaemia, disseminated carcinomatosis (Girdwood, 1959), myelofibrosis (Chanarin, Mollin, and Anderson, 1958), and haemolytic anaemia (Chanarin, Dacie, and Mollin, 1959). The presence of megaloblastic erythropoiesis in myelofibrosis has been described in only ...

BACKGROUND Magnetic nanoparticles show great promise for use as tools in a wide variety of biomedical applications. The purpose of this study was to investigate the potential effects of methacrylamido-folic acid (Ma-Fol)-modified magnetic nanoparticles on 5RP7 (H-ras-transformed rat embryonic fibroblasts) and NIH/3T3 (normal mouse embryonic fibroblasts). METHODS The cytotoxicity and viability...