BACKGROUND Uric acid (UA) is an endogenous antioxidant which is known to reduce oxidative stress and also chelate iron ion. Recent studies have provided evidence that UA may play a neuroprotective role in Parkinson's disease (PD). However, it is unknown whether UA relates to nigral iron deposition, which is a characteristic pathophysiological alteration in PD. The aim of this study was to deter...

Neisseria meningitidis is able to chelate iron from human transferrin (HTF), the main sequestrator of extracellular iron in vivo. Previous workers have reported that a ca. 70 kilodalton (kDa) iron regulated outer membrane protein (FeRP-70) is a highly specific receptor for HTF. We have examined the interaction between the iron regulated outer membrane proteins (OMP's) and HTF, using HTF and rab...

Nontransferrin-bound iron (NTBI) is a heterogeneously speciated plasma iron, typically detectable when transferrin saturation (TfSat) exceeds 75%. Here, we examine factors affecting NTBI levels by a recently discovered direct chelator-based (CP851) fluorescent bead-linked flow-cytometric assay (bead-NTBI), compared with the established indirect nitrilotriacetate (NTA) assay in 122 iron-overload...

A kind of environmental friendly novel composite flocculants which are used to treat raw water is prepared. It is made with chitosan (CS), iron modified polyaluminium chloride (CF-PAC) and modified montmorillonite on the principle of “the combination of organic and inorganic”. Under the optimum best compound formula and flocculation process, the turbidity of the waste water reduced by 0.62%, th...

tow new compound of type [(chelate)2cu-oh-cu(chelate)2] x3.nh2o, where chelate=1,10-phenanthroline; x=cl¯(n=3.5) and chelate=4,4'-dimethyl-2,2'-bipyridine;  (n=5) have been synthesized and their properties investigated. the complexes show room temperature magnetic moment order of 1.0 b.m. per copper atom. the x-band esr spectrum of powdered samples at room temperature shows typical dm=1 transit...

The oxidation of amino acids by Fenton reagent (H2O2 + Fe(II] leads mainly to the formation of NH+4, alpha-ketoacids, CO2, oximes, and aldehydes or carboxylic acids containing one less carbon atom. Oxidation is almost completely dependent on the presence of bicarbonate ion and is stimulated by iron chelators at levels which are substoichiometric with respect to the iron concentration but is inh...

Siderophores (ferric ion chelators) are secreted by organisms in response to iron deficiency. The pathogenic enterobacterium Erwinia chrysanthemi produces two siderophores, achromobactin and chrysobactin (CB), which are required for systemic dissemination in host plants. Previous studies have shown that CB is produced in planta and can trigger the up-regulation of the plant ferritin gene AtFER1...

Despite renewed interest in carbon dioxide (CO2) reduction chemistry, examples of homogeneous iron catalysts that hydrogenate CO2 are limited compared to their noble-metal counterparts. Knowledge of the thermodynamic properties of iron hydride complexes, including M-H hydricities (ΔGH(-)), could aid in the development of new iron-based catalysts. Here we present the experimentally determined hy...

Calcutta 700054, India 50 pM Fe3+. The siderophore was purified and characterized as containing 2,3dihydroxybenzoic acid (DHBA) as the core compound and threonine as i ts conjugate. The siderophore was able to reverse growth inhibition of the strain induced by ethylenediamine-di(o-hydroxyphenyl-acetic acid) (EDDA). A highaff ini ty iron-transport system capable of transporting 59Fe-siderophore ...

Absorption of iron by plants can be increased by adding a chelating azent to a soil (2, 7, 24). Jacobson (9) found that 5 or 10 ppm of iron supplied as FeEDTA in solution cultures provided adequate iron to the plant at high pH. Other workers (7, 11, 12, 19, 20, 23, 24, 25) have confirmed these observations. Plant responses to chelate applications have been shown to differ between plant species ...