The pattern of contralaterally and ipsilaterally projecting retinal ganglion cell (RGC) axons at the optic chiasm is essential for the establishment of binocular vision. Contralateral axons cross the chiasm midline as they progress from the optic nerve to the optic tract. In contrast, ipsilateral axons deviate from the chiasm and continue in the ipsilateral optic tract, avoiding the chiasm midl...

It is well established that the discharge of neurons in primate motor cortex is tuned to the movement direction of the contralateral arm. Interestingly, it has been found that these neurons exhibit a directional tuning to the ipsilateral arm as well and that the preferred directions to both arms tend to be similar. A recent study showed that motor cortex cells are also directionally selective t...

Previous studies of cortical retinotopy focused on influences from the contralateral visual field, because ascending inputs to cortex are known to be crossed. Here, functional magnetic resonance imaging was used to demonstrate and analyze an ipsilateral representation in human visual cortex. Moving stimuli, in a range of ipsilateral visual field locations, revealed activity: (i) along the verti...

In newborn rats each retina projects principally to the contralateral superior colliculus, but there is also a sparse projection to the whole of the ipsilateral superior colliculus. During the first 2 weeks postnatally the ipsilateral projection normally becomes restricted to the rostromedial part of the superior colliculus. The restriction of this projection is due to the preferential death of...

BACKGROUND AND PURPOSE Cerebral occlusive vascular disease is an established risk factor for ischemic stroke; however, little is known about its effects on brain function in patients without stroke. To detect possible functional alterations, we used magnetoencephalography and evaluated cerebral cortical activity during hand motor tasks in a group of such patients. Method- Event-related desynchr...

The ipsilateral primary motor cortex (M1) plays a role in voluntary movement. In our studies, we used repetitive transcranial magnetic stimulation (rTMS) to study the effects of transient disruption of the ipsilateral M1 on the performance of finger sequences in right-handed normal subjects. Stimulation of the M1 ipsilateral to the movement induced timing errors in both simple and complex seque...

Transient focal cerebral ischaemia can cause neuronal damage in remote areas, including the ipsilateral thalamus and subsutantia nigra, as well as in the ischaemic core. In the present study, we investigated long-term changes in the ipsilateral substantia nigra from 1 up to 20 weeks after 90 min of transient focal cerebral ischaemia in rats, using tyrosine hydroxylase (TH), neuronal nuclei (Neu...

Neuropathic pain is an intractable problem in clinical practice. Accumulating evidence shows that electroacupuncture (EA) with low frequency can effectively relieve neuropathic pain. Transient receptor potential vanilloid type 1 (TRPV1) plays a key role in neuropathic pain. The study aimed to investigate whether neuropathic pain relieved by EA administration correlates with TRPV1 inhibition. Ne...

OBJECTIVE To characterize the development of ipsilateral corticospinal projections from birth and compare to 1) development of contralateral projections in the same subjects and 2) ipsilateral corticospinal projections in subjects with unilateral lesions of the corticospinal system acquired perinatally or in adulthood. METHOD Transcranial magnetic stimulation excited the motor cortex, and res...

The visuotopic organization of the superior colliculus of normally pigmented and Siamese cats was investigated with microelectrodes. In normal cats, the represen­ tation of the ipsilateral hemifield in the rostral tectum was found to be binocular. In addition, this representation included more of the ipsilateral hemifield than has been previously reported. Both normally pigmented and Siamese ca...