Nocturia is a major problem in geriatric patients. Clock genes regulate circadian bladder function and Piezo type mechanosensitive ion channel component 1 (Piezo1) that senses fullness. We utilized WT mutant (ClockΔ19/Δ19: nocturia phenotype) mice to determine if the effects of GsMTx4, Piezo1 inhibitor, dependent on expression bladder. compared voiding behavior after administration vehicle, low...

In this paper an IP based network consisting of two separate networks - a virtual one, running MPLS and experimental network, connected to the have been studied. VoIP traffic is exchanged between networks. Both are Internet exchange with it. The created by using GNS3. purpose show comparison in performance addition, mathematical distributions approximations made be used further evaluate methodo...

The ability to generate crew pairings quickly is essential to solving the airline crew scheduling problem. Although techniques for doing so are well-established, they are also highly customized and require significant implementation efforts. This greatly impedes researchers studying important problems such as robust planning, integrated planning, and automated recovery, all of which also requir...

Highly symmetric problems result in redundant search effort which can render apparently simple problems intractable. Whilst the potential benefits of symmetry-breaking have been explored in the broader search and constraint satisfaction community (see (Gent & Smith 2000; Ip & Dill 1996; Crawford et al. 1996) for examples) there has been relatively little interest in the exploitation of this pot...

The development of networks for converged services including voice, video and data over the same infrastructure requires appropriate planning and dimensioning. This work presents a methodology, based on discrete event simulation, that supports the dimensioning and planning of IP multi-service links with QoS requirements. One key aspect is the type of traffic considered: stream, which has strict...

The objective of this study was to determine the chemical compounds of Iranian propolis (IP) extracts and to show flavonoids and phenol effects on methane production, fermentation characteristics and rumen microbial population (in vitro). In this study two diets with different concentrate: forage ratios as (HC: high concentrate) and (MC: middle concentrate), respectively as non-supplemented or ...

This thesis focuses on designing automatic planning tools for the planning problem of 3rd Generation (3G) Universal Mobile Telecommunication System (UMTS) all-IP Release 4 networks. A new mathematical model for the design problem of such architecture was proposed. The main advantage of the proposed model is to incorporate a realistic traffic profile taken from real live networks. Two approximat...