A redistricting plan partitions a state’s tracts (often counties or census tracts) into a set of congressional districts. Special interests attempt to mold districts to their political advantage, often inviting judicial review in the process. The quality of a plan has been judged by the courts using a fairly standard set of criteria: (1) the districts must be contiguous, (2) the districts must ...

Background A common method of recruiting for randomized trials is to send letters to potentially eligible patients inviting them to a screening appointment. In 3 consecutive UK studies the proportion attending from those invited fell from 49% [1] in 1994-1997 and 42%[2] in 1998-2001 to 13% at the beginning of an ongoing study in 2007. Procedures were similar in the 3 trials except that in 2007 ...

The exo-enzyme autotaxin/NPP2 (ATX/NPP2) is a potent stimulator of cell migration, invasion, metastasis, and angiogenesis. Recently, ATX/NPP2 was found to possess lysophospholipase D (lyso-LPD) activity, generating the bioactive mediator lysophosphatidic acid from precursors. In the present study, we used site-directed mutagenesis to delineate the active domain of lysophospholipid catalytic act...

This chapter summarizes the common errors haunting the beginner modelers. Modeling is a tricky, error-inviting business, as you would probably agree through doing the homework problems. The errors can be as small as a typo, or as big as capturing the relationships between quantities incorrectly (i.e. making a wrong flowchart to start with). Some errors are easily detected and reported by Berkel...

the asia pacific journal of medical toxicology (apjmt) was born in december 2012 to open up new perspectives for dissemination of research in medical toxicology. it was also created to expand the science of medical toxicology, addiction morbidities, drug interactions and adverse effects in the asia pacific region (1,2). the journal has attracted the support of medical toxicologists from differe...

The feeling of being utterly lost that is cultivated by David Lynch’s Inland Empire (2006), one a handful films central to Dominic Lash’s Cinema Disorientation: Inviting Confusions, might be the paradigmatic effect body work Lash refers as “cinema disorientation”. These insistently problematise viewer’s relation unfolding diegesis, leaving them without stability interpretive points re...

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