Blood vessel growth is a fascinating example of an adaptive, morphologically plastic network formation process driven by complex interactions between individual cells in the vessel and between the cells and their dynamic extracellular environment. Under normal conditions this can generate a well-adapted hierarchical branching structure. However in tumours, blood vessels become maladapted, leaky...

• In 2007, the U.S. provided $257 million in funding for bilateral programs to fight malaria. Twenty‐five million people, most of these children, in 15 countries have been reached through these investments. • The U.S. has disbursed more than $2.5 billion to the Global Fund to Fight AIDS, Tuberculosis, and Malaria, a key partner in the fight against malaria, since its inception. The Global Fund ...

Fungi are associated with a wide spectrum of diseases in humans, with increasing morbidity and mortality [1]. Therefore, it is of great importance to elucidate the genetic and immunological mechanisms underlying the susceptibility to fungal infections. Recent studies of primary immunodeficiencies (PIDs)—a group of hereditary immune disorders with increased susceptibility to infection—have led t...

If we compare the postuons of public authorities concerning the regulation of the use of tobacco worldwide, we fmd three situations. Some countries, usually those in which tobacco is not cultivated or processed, have adopted and enforced strict legislation in order to safeguard the health of their citizens, for example, Finland and Norway. Elsewhere, there are powerful commercial interests in t...

My previous editorial lamented the apparent decision by the federal government not to proceed with the introduction of new warning labels on cigarette packs. However, at the same time that the November-December issue of the Journal was coming off the presses at the printing house, Health Minister Leona Aglukkaq announced December 30 th that current labels would indeed be replaced by larger and ...