BACKGROUND AND PURPOSE Reperfusion injury can be revealed as delayed gadolinium enhancement in the subarachnoid space on a fluid-attenuated inversion recovery image, which is designated as a hyperintense acute reperfusion marker (HARM). We sought to investigate the occurrence and predictors of HARM and its association with new ischemic infarcts after carotid revascularization. METHODS Forty-f...

Background On delayed-enhancement (DE-CMR), both fat and infarcted myocardium appear bright making them difficult to differentiate. Standard chemical shift fat-suppression (FatSatCS) consists of a fat-frequency selective saturation followed by readout. This approach is suboptimal in clinical DE-CMR sequences which typically have long readout times (100-200ms) and as a result, fat magnetization ...

Efficient acquisition strategies for magnetization-prepared imaging based on the three-dimensional (3D) stack-of-rings k-space trajectory are presented in this work. The 3D stack-of-rings can be acquired with centric ordering in all three dimensions for greater efficiency in capturing the desired contrast. In addition, the 3D stack-of-rings naturally supports spherical coverage in k-space for s...

INTRODUCTION: T2prep Inversion Recovery [1] (T2IR) is a hybrid magnetization preparation technique that combines two well-known preparations, T2prep and Inversion Recovery, to provide contrast between tissues with similar T1 but different T2 relaxation times. This unique property has been utilized in vessel wall imaging where the wall-lumen contrast needs to be maximized for accurate diagnosis....

BACKGROUND AND PURPOSE Corpus callosum lesions are of specific interest in the evaluation of suspected multiple sclerosis in brain MR imaging. Using thin-section sagittal fluid-attenuated inversion recovery images, researchers have shown that the finding of "subcallosal striations" correlates significantly with the diagnosis of multiple sclerosis. Using the same MR imaging technique, we describ...

BACKGROUND AND PURPOSE Lesion volume measurements in disabling ischemic stroke have excellent reliability, but it is not clear whether this is also true for small lesions. We assessed the reliability of measuring baseline and follow-up lesion volumes in transient ischemic attack and minor stroke. METHODS Patients who presented with a transient ischemic attack or minor stroke (NIHSS < or = 3) ...

Background Chemical shift based water-fat separation methods can be used to reconstruct simultaneous fat and water images, thereby improving the sensitivity of fat detection using a positive fat contrast. The presence of fatty infiltration is a hallmark pathological feature of arrhythmogenic right ventricular cardiomyopathy (ARVC). Furthermore, the presence of fatty infiltration in chronic myoc...

BACKGROUND AND PURPOSE Intraprocedural transcranial Doppler sonography has identified multiple microembolic events during and immediately after carotid endarterectomy (CEA) or angioplasty, yet the rate of clinically evident stroke is small. To determine the significance of the transcranial Doppler sonography findings, we examined patients by use of diffusion-weighted imaging and fluid-attenuate...

The longitudinal relaxation time constant (T1) of the myocardium is altered in various disease states due to increased water content or other changes to the local molecular environment. Changes in both native T1 and T1 following administration of gadolinium (Gd) based contrast agents are considered important biomarkers and multiple methods have been suggested for quantifying myocardial T1 in vi...

Investigators from the Mayo Clinic, Rochester Minnesota investigated the utility of three-dimensional (3D) double inversion recovery (DIR) sequences in magnetic resonance imaging (MRI) detection of focal cortical dysplasia (FCD) in children and young adults with epilepsy.