PURPOSE To report crystal formation as a complication of intravitreal ganciclovir injection. PATIENTS AND METHODS A 73-year-old female patient with unilateral cytomegalovirus retinitis was treated with intravitreous ganciclovir (4 mg/0.04 mL). RESULTS After the intravitreal injection, sudden crystallization was observed in the vitreous humor. The patient experienced marked reduction in visu...

PURPOSE To assess the short-term safety and efficacy of an intravitreal injection of bevacizumab in a patient with neovascular glaucoma. CASE REPORT Intravitreal bevacizumab injection was given in a patient with neovascular glaucoma and the changes in the visual acuity, intraocular pressure (lOP), iris neovascularisation were noted before injection and after one day, one week, three weeks and...

Diabetic macular edema is considered the most important factor related to visual impairment in patients with diabetic retinopathy. Together with the use of grid and focal laser photocoagulation, today the intravitreal administration of pharmacotherapies represents the standard of care for the treatment of this complication: anti-vascular endothelium growth factor agents and steroids are the dru...

To assess the potential visual benefit of intravitreal bevacizumab in a patient with macular edema from idiopathic retinal vasculitis, aneurysms, and neuroretinitis, an intravitreal injection of bevacizumab (1.25 mg) was given. Within 1 week, visual acuity improved from 20/60 to 20/30 and optical coherence tomography demonstrated resolution of macular edema. There was no adverse effect. The mac...

To study its safety and efficacy in treating cytomegalovirus (CMV) retinitis, an AIDS patient received an intravitreal injection of liposome encapsulated ganciclovir in the right eye. The left eye served as a control, receiving intravitreal free ganciclovir. The right eye showed no retinal haemorrhages or detachment; however, vision declined initially, stabilising later. Weekly examination show...

Intravitreal triamcinolone is administered for a wide number of vitreoretinal conditions. Several complications including cataract formation, raised intraocular pressure, and endophthalmitis have been reported following intravitreal injections. We report a rare case wherein triamcinolone was inadvertently injected directly into the crystalline lens. A 41-year-old male presented to us with a his...

diabetic macular edema (dme) is a leading cause of vision loss in the working-age population worldwide. numerous early studies suggest an important role for intravitreal anti-vegf agents such as bevacizumab in the management of dme. we reviewed manuscripts that had investigated pharmacokinetic, efficacy, safety, dose and frequency of intravitreal bevacizumab (ivb) injections as well as effect o...

INTRODUCTION Although laser photocoagulation is the primary treatment for diabetic macular oedema, treatment of eyes with diffuse macular oedema has been disappointing. Intravitreal injection of steroids is being investigated for the treatment of diabetic macular oedema. Preliminary results indicate that steroid injections do improve macular oedema, but it is not clear if they improve visual ac...

Background — Intravitreal implants solve a number of serious problems arising in diseases the posterior segment eyeball. Unlike intravitreal injections, implant provides prolonged release pharmaceutical drug over time. The review presents characteristics existing systems for delivery: nanosystems, non-biodegradable and biodegradable implants. also highlights main advantages disadvantages variou...

We report a case of bilateral Eales’ disease managed with intravitreal bevacizumab. A 32-year-old woman history bacillus Calmette-Guerin vaccine, administered when she was 10 years old, presented five-day scotoma in the temporal field her right eye. dilated fundus exam and fluorescein angiography showed retinal peripheral capillary non-perfusion, neovascularization eye, deep intraretinal hemorr...