conclusions according to the results, the old dosimetry formalisms, overestimate the dose especially towards the applicator’s tip. while the tg-43u1 based software perform the calculations more accurately. results for a typical arrangement of 10 active pellets in the applicator, the percentage difference between doses obtained by the new algorithm at 1cm distance from the tip of the applicator ...

Brachytherapy (derived from the Greek term brachios, meaning short) is defined as the treatment of tumors through the placement of radioactive sources into or close to the malignant lesion. The main advantage of brachytherapy is based on the inverse squared law inherent to radioactive sources, which allows the delivery of a very high dose of radiation to the tumor with a substantial sparing of ...

We consider the inverse planning problem in brachytherapy, i.e. the problem to determine an optimal number of catheters, number of sources for low-dose rate brachytherapy (LDR) and the optimal dwell times for high-dose rate brachytherapy (HDR) necessary to obtain an optimal as possible dose distribution. Starting from the 1930s, inverse planning for LDR brachytherapy used geometrically derived ...

PURPOSE In an effort to shed light on the continuing debate over the best treatment options for patients with localized prostate cancer, we present a retrospective review of patients from a single group community urology practice. METHODS AND MATERIALS Data from 1707 patients were reviewed. These patients, with T1 or T2 adenocarcinoma of the prostate, were treated from 1992 to 2004 with eithe...

Bladder cancer has been observed in patients after permanent iodine-125 brachytherapy （hereafter referred to as brachytherapy） for prostate cancer. We investigated secondary bladder brachytherapy. From January 2005 March 2021, a total of 1,478 underwent localized at Showa University Hospital and Koto Toyosu Hospital. A standardized incidence rate was calculated from the compared with national r...

This review summarizes the current understanding of the feasibility of functional imaging for brachytherapy. In following subsections the role of ultrasound, power doppler imaging, positron emission tomography, magnetic resonance imaging, dynamic dose calculation and targeted brachytherapy is analyzed. The combination of functional imaging with the new tools for intraoperative dose calculation ...

Radiotherapy is an integral component of management of high-grade soft tissue sarcomas. Interstitial brachytherapy is used to deliver a boost or radical dose with several advantages over external beam radiotherapy. There has always been a concern to use brachytherapy with flap reconstruction of skin defects after wide excision. We preset our initial experience with interstitial brachytherapy in...

Both primary and recurrent squamous cell carcinoma of the head and neck are classic indications for brachytherapy. A high rate of local tumor control at the cost of limited morbidity can be achieved with brachytherapy through good patient selection, meticulous source implantation and careful treatment planning. However, no randomized trials have been performed, and there is scant evidence in th...

PURPOSE To evaluate gold marker displacement due to needle insertion during HDR-brachytherapy for therapy of prostate cancer. PATIENTS AND METHODS 18 patients entered into this prospective evaluation. Three gold markers were implanted into the prostate during the first HDR-brachytherapy procedure after the irradiation was administered. Three days after marker implantation all patients had a C...