showed significant changes in frequencies >8 kHz that were not detected with the routine pure tone audiometry and distortion product otoacoustic emission audiodiagnostic tests. In conclusion, although the idea of such studies about the otoprotective effect of intratympanic injections against cisplatininduced ototoxicity seems magnificent and deserves more modifications, a careful revision in ev...

– Being a prospective study makes serial data collection possible, checking the anatomophysiologic status of these little patients’ middle ears monthly. Thus, in contrast with traditional cross-sectional studies it offers us accurate data on the incidence of otitis media with effusion during the first 2 years of life, the dynamic behavior of the middle ear/auditory tube complex and the delicate...

objective(s) the aim of this study was to evaluate the effects of dexamethasone on striatal dopaminergic, glutamatergic and gamma amino butyric acid (gaba) ergic neurotransmission in normal and parkinsonian rats. materials and methods dexamethasone (0.15, 0.30, 0.60 and 0.8 mg/kg) was administered to normal or parkinsonian rats (i.p.) followed by the analysis of the striatal neurotransmitters c...

conclusions dexamethasone 8mg is a better anti-emetic agent than metoclopramide for the prevention of post-operative nausea and vomiting after laparoscopic cholecystectomy. objectives this study evaluates the prophylactic anti-emetic effect of dexamethasone in comparison with metoclopramide and placebo for the prevention of post-operative nausea and vomiting in patients undergoing elective lapa...

background croup, or acute laryngotracheobronchitis, is the most common cause of upper airway obstruction in children. objectives in this study, the efficacies of intramuscular and oral dexamethasone administration are compared for treatment of croup. patients and methods this is a single-blind randomized trial involving 68 children divided into two groups, the first group received 0.6 mg/kg in...

salivary mucocele is a common lesion derived from minor salivary glands with various surgical or non-surgical treatment modalities. to evaluate the effect of a highly potent corticosteroid (dexamethasone) in the management of salivary mucocele, we performed intralesional injection of dexamethasone in nine patients with labial mucocele. complete healing of lesions observed in seven of nine patie...

Introduction: Postoperative sore throat is a common complaint in patients with endotracheal intubation and has potentially dangerous complications. This randomized controlled trial study investigated the incidence of postoperative sore throat after general anesthesia when betamethasone gel is applied to a tracheal tube compared with when IV dexamethasone is prescribed.   Materials and Methods: ...

Background and Aims: Diabetes is one of the most important endocrine disrupters and is associated with various hormones, including those that can lead to diabetes. Glucocorticoid use may lead to insulin resistance. Dexamethasone is one of these glucocorticoid compounds. Glutamate dehydrogenase plays a key role in the production of glutamate in the secretion of insulin. Based on these hormonal i...

background and aims: laryngospasm and vomiting occurring after tracheal extubation in children is potentially dangerous. the aim of this study was to investigate the effects of preoperative 0.5 mg/kg i.v. dexamethasone on the incidence of postextubation laryngospasm, and vomiting in children after tonsillectomy.material and methods : this study was performed at the ilam imam khomeini hospital, ...