Purpose Whether preconception elevated concentrations of thyroid-stimulating hormone (TSH) compromises reproductive outcomes in patients undergoing assisted reproduction techniques (ARTs) remains unclear. This study therefore compared the reproductive outcomes in patients with TSH concentrations of < 2.5 mIU/L, 2.5-4.0 mIU/L, and 4.0-10.0 mIU/L undergoing controlled ovarian stimulation (COS) fo...

A 58-year-old white female had severe bone pain for 1 week. Increased levels of free l light chain (2423 mg/L) were present in the serum with decreased levels of all immunoglobulins. The complete blood count and differential were within normal limits. The peripheral blood smear had increased rouleaux formation and atypical plasma cells containing numerous cytoplasmic Russell bodies (panel A). T...

An established human neurogenic sarcoma cell line pre sented a tumor-associated antigen common to various sarcoma tumors. The antigen was detected by immunofluorescent techniques with the use of the sera of patients bearing such tumors and is located mainly on the cellular surface. The tumor-specific antibody of most sera showed only membrane immunofluorescence while five sera revealed both int...

INTRODUCTION The presence of eosinophilic bodies in a skin biopsy can be found in a variety of situations and this may present a challenge to the pathologist. The differential diagnosis of these eosinophilic structures include microorganisms such as histoplasmosis or cryptococcosis, fungi, Michaelis-Gutmann bodies, deposits of amyloid or immunoglobulins, colloid bodies or elastic bodies. CASE...

It was reported that recombinase-A protein (RecA)-coated exogenous DNA was more likely to be integrated into mouse, goat and pig genomes. The objective of this study was to investigate whether integration of exogenous DNA into the rat genome is improved by the recombinase-mediated DNA transfer. Pronuclear microinjection of RecA-coated EGFP or OAMB DNA resulted in a production efficiency of tran...