We present a novel microscopic tridomain model describing the electrical activity in cardiac tissue with dynamical gap junctions. The system consists of three PDEs modeling conduction intra-and extra-cellular domains, supplemented by nonlinear ODE for dynamics ion channels and establish global existence uniqueness weak solutions to our model. solution, which constitutes main result this paper, ...

The yeast Saccharomyces cerevisiae exhibits sustained oscillations under noise-free controlled conditions in continuous cultures. The regular periodicity of the oscillations and synchrony between different metabolic variables may be described by mathematical models and model-based control. Large bioreactors, however, are prone to disturbances or noise in the feed stream, which may alter the osc...

the interaction of dppa which is an important component in cellular membrane with molecules of water asmedia, cause some changes in geometry of dppa .in this study we focused our attention on comparing thismolecule with related hydrated complexes employing different basis sets at hartree-fock levels of theory. thetheoretical nmr shielding tensor of some imported atoms were also reported.

Background Interactions between the Aβ with intra- and extra-cellular molecules disrupt neuronal structures functions, leading to cognitive dysfunction in Alzheimer’s disease (AD). We previously have shown that competitively inhibits microtubule motor protein KIF11 (Kinesin-5/Eg5), which regulates dynamics, cellular trafficking, migration, important for learning memory. In vitro cell culture ex...

Purpose: The aim of the study was to propose a theory based on topology and geometry diffusion channels in tissue contribute mechanistic understanding normal sparing at ultra-high dose rates (UHDRs) explore an interplay between intra- inter-track radical recombination through reaction–diffusion mechanism. Methods: We calculate time evolution particle track structures using system coupled equati...

Water supply surveillance generates data on the safety and adequacy of drinking water supply in order to contribute to the protection of human health. Most current models of water supply surveillance for urban areas come from developed countries and have significant shortcomings if directly applied elsewhere. There are differences not only in socio-economic conditions but also in the nature of ...

We present the first experimental vibrational spectroscopy study providing direct evidence of a water phase inside single-walled carbon nanotubes that exhibits an unusual form of hydrogen-bonding due to confinement. Water adopts a stacked-ring structure inside nanotubes, forming intra- and inter-ring hydrogen bonds. The intra-ring hydrogen bonds are bulk-like while the inter-ring hydrogen bonds...

specific and non- specific cellular immune responses were studied in 20 amoebiasis cases and 10 controls. all the study cases and controls were indians living in varanasi, india. ten amoebic liver abscess cases were patients admitted to university hospital. ten non-invasive intestinal amoebiasis cases constituted the second study group. non-specific immune responses were studied using e-rosette...

objective(s) the central nucleus of the amygdala (cea) is a forebrain structure which is important in regulation of ingestive behavior and there is direct and circumstantial evidence to indicate that some circuits involved with feeding behavior include glutamatergic elements. the present study examined whether administration of nma (n-methyl-dl-aspartic acid) or mk801 into the cea altered water...