Acute macular neuroretinopathy is an infrequently encountered condition in which there is a sudden mild central vision loss, photopsia and red-brown wedge-shaped lesions in the macular region with corresponding scotomata in the central visual fields. The condition may be associated with the use of oral contraceptives or with a recent febrile illness. It is self-limiting and non-recurrent. The c...

This article argues that the mid-1960s saw a dramatic shift in how 'brainwashing' was popularly imagined, reflecting Anglo-American developments in the sciences of mind as well as shifts in mass media culture. The 1965 British film The Ipcress File (dir. Sidney J. Furie, starr. Michael Caine) provides a rich case for exploring these interconnections between mind control, mind science and media,...

Crohn’s disease (CD) is a chronic recurrent inflammatory bowel with wide variety of clinical manifestations – from classical gastrointestinal phenotypes to predominance extraintestinal symptoms. Atypical course CD observed relatively often and manifested damage almost all body systems, including hepatobiliary, immune, hematopoietic, cardiovascular, nervous, as well eyes, skin, lungs kidneys. ma...

background: crohn’s disease is an inflammatory bowel disease that can affect any part of the gastrointestinal (gi) tract including the mouth. bowel symptoms are predominant. oral involvement may precede the gi symptoms. this case report presents a patient affected by crohn’s disease with oral onset. case presentation: we present a 30-year-old pregnant woman complaining of chronic, multiple, yel...

BACKGROUND The treatment policy and disease process of mucosa-associated lymphoid tissue (MALT) lymphomas are different from those of other gastrointestinal lymphomas. Chemotherapy has replaced curative surgery as the treatment of choice in gastric lymphomas but the optimal frontline treatment of intestinal lymphomas has yet to be defined. Hence, we attempted to identify the difference in featu...

BACKGROUND Hnf4alpha, an epithelial specific transcriptional regulator, is decreased in inflammatory bowel disease and protects against chemically-induced colitis in mice. However, the precise role of this factor in maintaining normal inflammatory homeostasis of the intestine remains unclear. The aim of this study was to evaluate the sole role of epithelial Hnf4alpha in the maintenance of gut i...

The infant’s immature intestinal immune system develops as it comes into contact with dietary and microbial antigens in the gut. The evolving indigenous intestinal microbiota have a significant impact on the developing immune system and there is accumulating evidence indicating that an intimate interaction between gut microbiota and host defence mechanisms is mandatory for the development and m...