Pigs were exposed to three passages of the NADC-8 strain of porcine reproductive and respiratory syndrome virus (PRRSV) to investigate the relationship between genotypic and phenotypic properties. Differences were found in the virulence of the three passages called virulent, intermediate, and avirulent. Avirulent virus was derived by attenuation of virulent virus in cell culture and intermediat...

one manifestation of the idiopathic hypercalcaemia of infancy syndrome, and the possible aetiologies are discussed. Another presentation of supravalvar aortic stenosis is in the so-called familialform, but there may exist considerable confusion between these two forms, as less than 50 per cent of those without physical stigmata have a positive family history, and the severeform of the idiopathi...

We determined the outcome of patients with myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia (sAML) after allogeneic stem cell transplantation according to their international prognostic scoring system (IPSS) risk categories at diagnosis. A total of 11 females and 7 males, with a median age of 45 years, were transplanted. With a median follow-up of 60 months, the 6-year actuar...

We reviewed the clinical features, outcome, and treatment of many of the epileptic syndromes that begin in the childhood from 2 to 12 years of age, using a review of the literature and personal experience, with most references to authoritative texts. The developmental tasks of childhood are centered on refinement of motor skills and development of complex intellectual and social skills. The chi...

Venous thromboembolism from a “thrombotic storm”–like syndrome is major cause of morbidity and mortality in patients with active or “recovered” COVID-19. Patients should be risk-stratified, optimally by pulmonary embolism (PE) response team (PERT), considered for escalation care if found intermediate high-risk PE. We present series COVID-19-associated PE thrombotic storm D-dimer >10 000 ng/m...

Frailty is associated with poor quality outcomes. To examine associations between frailty and hospital readmission or mortality in Coronary Heart Disease (CHD). Retrospectively assessed the 2016 US Nationwide Readmissions Database (NRD) including adults ≥ 65 years pre-existing CHD. A validated Hospital Risk Score (HFRS) using ICD-10-CM codes identified risk. Outcomes included: Readmission (30-d...

BACKGROUND Little is known about the alveolar dead-space fraction after the first week of acute respiratory distress syndrome (ARDS). We measured the dead-space fraction in the early phase (first week) and the intermediate phase (second week) of ARDS, and evaluated the association of dead-space fraction with mortality. METHODS We prospectively measured dead-space fraction and other variables ...

Introduction. Tumor lysis syndrome is an emergency condition requiring prompt recognition and treatment. It?s a consequence of spontaneous or therapy-induced cellular death leading to the release intracellular ions metabolic products purine bases into bloodstream. Pathophysiology. The characteristic derangement comprises hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia. These change...

A model is developed to study the in vivo intermediate filament organization in terms of repartition between four different structural states: soluble proteins, particles, short, and long filaments. An analysis is conducted, showing that the system has a unique, globally asymptotically stable equilibrium. By means of sensitivity analysis, the influence of parameters on the system is studied. It...

Test method facet is one of the factors which can have an influence on the test takers’ performance. The purpose of the current study was to investigate the effects of two different response types, multiple-choice cloze and multiple-choice test, on the pre-intermediate and intermediate test takers’ reading comprehension performance. To this end, 40 pre-intermediate and intermediate learners par...