OBJECTIVE: The purpose of this study is to investigate the immunomodulatory effect beta glucan in an experimental model intraabdominal bacteremia induced by S. aureus.MATERIAL AND METHODS: Thirty Wistar albino rats were randomly divided into four groups. Staphylococcus aureus (SAB), treatment with cefazolin, glucan, both cefazolin and groups constituted respectively. 4 mg/kg 100 given after 12x...

PURPOSE The levels of interleukin-6 (IL-6) are frequently elevated in sera from patients with advanced prostate carcinoma. Our main objective was to investigate changes in responsiveness to IL-6 and/or androgen that occur in LNCaP cells after long-term treatment with IL-6. This in vitro model could be of clinical relevance because of its similarity with late-stage prostate carcinoma. EXPERIME...

background: about 5–10% of patients with asthma suffer from poorly-controlled disease despite corticosteroid (cs) therapy. methods: 21 severe and 30 mild asthma patients were recruited and underwent collection of blood sample. we determined whether there were any differences in inflammatory biomarkers between severe and mild asthma patients or not.results: levels of interleukin-8 (il-8) and int...

We herein report a 75-year-old man who developed disturbed consciousness with polynuclear cell dominant pleocytosis and low glucose extremely high interleukin (IL)-6 levels in his cerebrospinal fluid. The biopsy specimen from right supraclavicular lymph node showed the infiltration of inflammatory cells positive for IgG, IgG4 IL-6. Prednisolone azathioprine administered under suspicion IgG4-rel...

To describe clinical characteristics, and perinatal outcomes of patients with a short cervix, in which intra-amniotic inflammation using AF Interleukin-6 (IL-6) concentration was measured. Series cases including pregnant between 17–32 weeks gestation cervix our institution January 2018 April 2021. A total 37 were identified, concentrations IL-6 measured nine patients. Retrieved data included ma...

Recent studies have established that sex hormones directly or indirectly affect T and B cells and macrophages by manipulating the production of cytokines. In this study the possibility of the effect of 5a-DHT on macrophage (MΦ) nitric oxide (NO) release via interleukin-l, 6 (lL-1β, IL-6) or tumor necrosis factor-a (TNFα) was investigated. The endogenous cytokines IL-1β, IL-6 and TNF-α were ...