Abstract Background Macrophages and inflammatory cytokines play important roles in bone fracture healing. However, the expression patterns of macrophages during healing under condition postmenopausal osteoporosis have not been fully revealed. Methods Tibia transverse was established 12 weeks after ovariectomy or sham operation 16-week old female mice. Tibias were harvested before 1, 3, 5, 7, 14...