نتایج جستجو برای: interleukin 23

تعداد نتایج: 280903  

Journal: :Blood 1984
A J Hapel H S Warren D A Hume

The cell lines FDC-Pl and 32D cl-23 have previously been used as unique indicators for the growth-promoting activity of interleukin-3. We show that FDC-Pl cells respond to granulocyte/macrophage colony-stimulating factor (GM-CSF, CSF-2) as well as to interleukin-3. In keeping with this finding, FDC-Pl cells express the macrophage-specific marker, F4/80. FDC-Pl cells do not, however, respond to ...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

To analyze the levels of inflammatory factor and safety in treating psoriasis with apremilast. We selected 200 cases patients under-treated our hospital from January 2021 to 2022, divided them into control group experimental at random, 100 cases, respectively. Control received normal treatment, while treated Compare both groups on factors, skin lesions adverse drug reactions. Before had no stat...

Aghigh Ziaeemehr Amir Asnaashari, Fatemeh Heidarnezhad Houshang Rafatpanah, Kiarash Ghazvini Narges Valizadeh Reza Basiri Roghayeh Ghezelsofla Seyed Abdolrahim Rezaee Somayeh Sobhani

Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 cells. It can recruit neutrophils and macrophages to the infected site in the lungs. IL-23 is one of the most important inducers of IL-17. In the...

Journal: :Journal of immunology 2008
Silke M Schulz Gabriele Köhler Nicole Schütze Jens Knauer Reinhard K Straubinger Alissa A Chackerian Ellen Witte Kerstin Wolk Robert Sabat Yoichiro Iwakura Christoph Holscher Uwe Müller Robert A Kastelein Gottfried Alber

IL-12 is essential for protective T cell-mediated immunity against Salmonella infection. To characterize the role of the related cytokine IL-23, wild-type (WT) C57BL/6 and p19(-/-) mice were infected systemically with an attenuated strain of Salmonella enterica serovar Enteritidis (S. Enteritidis). IL-23-deficient mice controlled infection with S. Enteritidis similarly as WT mice. Similar IFN-g...

2014
Sherry L. Kurtz Alicia Y. Chou Klara Kubelkova Daniel J. Cua Karen L. Elkins Ashlesh K. Murthy

Our laboratory's investigations into mechanisms of protective immunity against Francisella tularensis Live Vaccine Strain (LVS) have uncovered mediators important in host defense against primary infection, as well as those correlated with successful vaccination. One such potential correlate was IL-12p40, a pleiotropic cytokine that promotes Th1 T cell function as part of IL-12p70. LVS-infected ...

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