BACKGROUND Microbleeds (MBs), proposed as a biomarker for microangiopathy, have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear. CASE REPORT We describe two patients who developed warfarin-induced ICH at the site of MBs documented in previou...

background: intracerebral  hemorrhage (ich) is the  most fatal subtype  of stroke.  despite  limited effective therapy, there  is no  accepted clinical grading  scale to  predict  in- hospital  mortality,  especially  in developing  nations.  the purpose  of this study was to assess the  predictors  of in- hospital mortality among a sample of iranian patients  with spontaneous ich for use at th...

intra-cerebral hemorrhage (ich) is a particularly severe type of stroke accounting for 10–15 % of all strokes and is associated with a mortality rate of 30–50%. neuroinflammation contributes to ich-induced secondary brain injury and understanding the mechanisms causing neuroinflammation can be helpful to find new treatments of ich. recent studies demonstrated that toll like receptor 2 (tlr2) fo...

RCVS: Reversible Cerebral Vasoconstriction Syndrome; rtPA: recombinant tissue Plasminogen Activator; GCS: Glasgow Coma Scale; CT: Computed Tomography; ICH: Intracerebral Hemorrhage; MRI: Magnetic Resonance Imaging; MRR: MR Renography; ACA: Anterior Cerebral Artery; MIS: Minimally Invasive Surgery; TCD: Transcranial Doppler; ICU: Intensive Care Unit; MISTIE: Minimally Invasive Surgery plus rt-PA...

Background: Primary intracerebral Hemorrhage (PICH) is a devasting illness with high early mortality which causes 10 -12 percent of stroke cases. Survivors of PICH are at risk for recurrence of hemorrhage. We wanted to determine the frequency of recurrence of ICH in patients with PICH at Alzahra and Noor hospital Isfahan, Iran. Methods: A descriptive retrospective study was did on the hospital ...

BACKGROUND AND PURPOSE Hematomas that enlarge following presentation with primary intracerebral hemorrhage (ICH) are associated with increased mortality, but the mechanisms of hematoma enlargement are poorly understood. We interpreted the presence of contrast extravasation into the hematoma after CT angiography (CTA) as evidence of ongoing hemorrhage and sought to identify the clinical signific...

Previous Antiplatelet Treatment and Mortality in Patients With Intracerebral Hemorrhage To the Editor: Foerch et al1 reported that pretreatment with antiplatelet agents was not an independent risk factor of mortality and unfavourable outcome in patients with intracerebral hemorrhage (ICH). They studied 1691 patients with ICH and found that 26% of them were taking antiplatelet agents. Pretreatme...

BACKGROUND Intracerebral hemorrhage (ICH) is a disease with high mortality and a substantial risk of recurrence. However, the recurrence risk is poorly documented and the knowledge of potential predictors for recurrence among co-morbidities and medicine with antithrombotic effect is limited. OBJECTIVES 1) To estimate the short- and long-term cumulative risks of recurrent intracerebral hemorrh...

17beta-estradiol reduces cell death after global and focal ischemia and subarachnoid hemorrhage in rodents. Presently, we tested whether estrogen improves outcome after intracerebral hemorrhage (ICH) in male rats. Rats were implanted subcutaneously with 0.05, 0.25, or 0.50 mg pellets of estrogen (21-day release) or subjected to a sham procedure. Two weeks after implantation, they were given a s...

BACKGROUND Intracerebral hemorrhage (ICH) associated with warfarin sodium therapy is becoming more common as the use of this medication increases in the aging population. OBJECTIVE To delineate factors associated with early mortality, determine variables responsible for poor functional outcome, and evaluate possible reasons for expansion of hemorrhage and associated parenchymal edema. DESIG...