نتایج جستجو برای: inhibition proliferation

تعداد نتایج: 481256  

Journal: :DEStech Transactions on Environment, Energy and Earth Science 2017

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2003
Niels W C J van de Donk Diana Schotte Marloes M J Kamphuis Ariënne M W van Marion Berris van Kessel Andries C Bloem Henk M Lokhorst

PURPOSE Prenylation is essential for membrane localization and participation of proteins in various signaling pathways. The following study was conducted to examine the importance of protein farnesylation and geranylgeranylation for the regulation of lymphoma cell survival and proliferation. EXPERIMENTAL DESIGN Lymphoma cells were treated with the beta-hydroxy-beta-methylglutaryl-CoA reductas...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2011
Hannes M Findeisen Florence Gizard Yue Zhao Hua Qing Elizabeth B Heywood Karrie L Jones Dianne Cohn Dennis Bruemmer

OBJECTIVE Proliferation of smooth muscle cells (SMC) in response to vascular injury is central to neointimal vascular remodeling. There is accumulating evidence that histone acetylation constitutes a major epigenetic modification for the transcriptional control of proliferative gene expression; however, the physiological role of histone acetylation for proliferative vascular disease remains elu...

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