Naoxintong (NXT) is a Chinese Materia Medica standardized product extracted from 16 various kinds of Chinese traditional herbal medicines including Salvia miltiorrhiza, Angelica sinensis, Astragali Radix. Naoxintong is clinically effective in treating ischaemia heart disease. Nucleotide-binding oligomerization domain-Like Receptor with a Pyrin domain 3 (NLRP3) inflammasome has been critically i...

The fatal outcome in the case described was unfortunate but was undoubtedly largely attributable to the patient's respiratory condition. The great difficulty which may be encountered in closing the duodenal stump in the presence of massive infiltration must, however, be stressed. We are indebted to Dr. A. A. Miller for valuable assistance with the pathological studies and for helpful advice. RE...

The occurrence, nature, and pathogenesis of intestinal lesions were studied in a number of graft vs. host reaction (GVHR) conditions in mice, combining variations in the nature of the following: the F1 hosts (newborn or adult, normal or lethally irradiated), the injected parental T cells (mixed or selected subsets of Lyt2' or L3T4' cells), and the antigenic stimulus (semiallogeneic or restricte...

We present a comparative study of four product operators on weighted languages: (i) the convolution, (ii) the shuffle, (iii) the infiltration, and (iv) the Hadamard product. Exploiting the fact that the set of weighted languages is a final coalgebra, we use coinduction to prove that a classical operator from difference calculus in mathematics: the Newton transform, generalises (from infinite se...

Objective: To evaluate the effects of preincisional infiltration and intraperitoneal instillation of bupivacaine on early relief of pain after diagnostic laparoscopy. Design: Randomized, placebo, controlled-double blind study Setting: University teaching hospital. Materials and methods: Sixty three women with unexplained infertility, for whom diagnostic laparoscopy was performed under general a...

BACKGROUND HDLs have antiinflammatory and antioxidant properties in vitro. This study investigates these properties in vivo. METHODS AND RESULTS Chow-fed, normocholesterolemic New Zealand White rabbits received a daily infusion of (1) saline, (2) reconstituted HDL (rHDL) containing 25 mg apolipoprotein (apo) A-I and 50 mg of either 1-palmitoyl-2-linoleoyl phosphatidylcholine (PLPC) or 1,2-dip...

The purpose of this study was to explore whether there is a linkage between the infiltration of CD8(+) T cells and the risk of death from esophageal cancer. Cases of 70 consecutive patients in whom esophageal squamous cell carcinomas ( n = 33) or adenocarcinomas (n = 37) were R0-resected between 1993 and 1999 were reviewed. The presence of activated CD8(+) T cells was evaluated by quantitative ...

Intestinal ischemia/reperfusion (I/R) injury is considered to be associated with high morbidity and mortality rates. Osthole, a natural derivative of coumarin, has been shown to exert a variety of pharmacological and therapeutic effects under physiological and pathological conditions. In the present study, to investigate the protective effects of osthole against intestinal I/R injury, various d...

The chronological expression (over 24 h) of two adhesion molecules [intercellular adhesion molecule-1 (ICAM-1) and CD11b/CD18 (Mac-1)] and the extent of liver damage, including injury to sinusoidal endothelial cells (SECs) and hepatocyte apoptosis, were investigated under two conditions of rat liver ischemia-reperfusion (I/R) injury: reversible (30 min) and fatal I/R (60 min). The chronological...

Multimodal wound infiltration analgesic techniques have attracted growing interest for applications in total knee arthroplasty (TKA). A benefit of using wound infiltration instead of femoral nerve block (FNB) in a multimodal pain control regimen is the limitation of muscle strength impairment to the surgical area, which will focus the pain control effort and may provide the opportunity for easi...