ABSTRACT Introduction: Formation of gastric ulcer is a multifactorial process so that vascular changes, mucous secretion, gastric acid and gastrointestinal tract mucous biochemistry are involved in gastric ulcers. Despite therapeutic properties, ibuprofen as a non-steroidal anti-inflammatory drug (NSAID) can cause mucosal lesions in the stomach. In this study, the effect of Matri...

Simvastatin appeared to have additional benefits beyond their lipid lowering effects, which has led to interest in the use of this class of drugs outside the field of cardiovascular disease. Aim: This study aimed to investigate the possible gastroprotective effect of simvastatin against both indomethacin and cold restraint stress (CRS) induced gastric ulcers in rats and to study its effect on g...

Introduction: Fuligo Plantae (FP), the ash that sticks to bottom of pots or chimneys after weeds burn, has long been used for its hemostatic effects and treatment gastrointestinal bleeding. Nevertheless, active ingredient FP still needs be further explored. Methods: The microstructure, optical chemical properties FP-CDs were characterized. An alcohol-induced gastric ulcer model was utilized eva...

ingestion of ciprofloxacin can be associated with esophagitis and esophageal ulcer. we report a 46-yearold man with odynophagia and dysphagia following ciprofloxacin ingestion, with a glance on diagnosis and treatment. also, we propose recommendations for prevention of drug-induced esophagitis, according to shape, size, formulation and their etiologic role on esophagitis.

OBJECTIVE To investigate the preventive and therapeutic effects of Danshen Decoction on gastric ulcer in experimental animal models. METHODS The model of water immersion restraint stress ulcer in mice, and the models of acetic acid impaired gastric ulcer and pyloric ligation gastric ulcer in rats were established. The total gastric acid, the activity of pepsin and the amount of gastric wall b...

Objective: Nelumbo nucifera Gaertn. (Nymphaeceae) is a well known aquatic herb which has been extensively used traditionally for the treatment of different diseases. Therefore present study was designed to evaluate the anti-ulcer activity of methanolic extract of Nelumbo nucifera Gaertn. (Nymphaeceae) stalks. Methods: Anti-ulcer activity of methanolic extract of Nelumbo nucifera (100 mg/kg and ...

Hericium erinaceus is a famous tonic in oriental medicine. The gastroprotective effects of aqueous extract of H. erinaceus against ethanol-induced ulcers in Sprague Dawley rats were investigated. The possible involvements of lipid peroxidation, superoxide dismutase, and catalase were also investigated. Acute toxicity study was performed. The effects of aqueous extract of H. erinaceus on the ulc...

Most of the currently available oral antiulcer drugs for the treatment of peptic ulcer provoke detrimental adversative effects. Hence, the exploration for plant-derived products for the treatment of ulcer continues. Syringin, a phenylpropanoid glucoside found in the tepals of Musa Paradisiaca, has many biological properties, including as an antioxidant, immunomodulatory and antidiabetic agent. ...

Aim of the study: To determine the pharmacological activity relevant to ulcer healing of Acacia farnesiana (aroma) leaf, a folk medicine used in the treatment of Ulcer. Materials and Methods: MEAF extract was done by using soxhelet apparatus and was further subjected to screening of the qualitative analysis of phyto chemicals. Consequently the Methanolic extract of leaf was tested against ulcer...

Infection of the stomach and proximal duodenum with Helicobacter pylori induces inflammation with associated changes in the mucosa. Alterations in mucus structure and function, surface epithelial cell integrity, mucosal blood flow, and local mucosal neural and hormonal status have been observed following this infection. A proportion of subjects infected with H pylori develop duodenal ulcer dise...