the objective of the study was to develop a simple, specific and stability-indicating hplc method for the simultaneous determination of creatine phosphate sodium (cps) and its related substances in pharmaceutical formulation. separation of creatine phosphate sodium from its major process impurities and degradation products was achieved on a hypersil bds c18 column (250 × 4.6 mm, 5 μm) with an a...

A novel and sensitive stability-indicating RP-HPLC method for the quantitative determination of cefquinome sulfate has been developed. Chromatographic separation and quantitative determination were performed using a high-performance liquid chromatograph with UV detection. As the stationary phase a LiChroCART RP-18 column (5 microm particle size, 125 mm x 4 mm, Merck, Darmstadt, Germany) was use...

A stability-indicating method by micellar electrokinetic chromatography (MEKC) was developed and validated for determination of milnacipran (MNC) hydrochloride in capsules. The MEKC separation was performed in a fusedsilica capillary (40 cm x 50 μm i.d.), 30 kV voltage applied at 30 °C, using as background electrolyte solution 20 mM borate buffer (pH 8.8), 20 mM sodium dodecyl sulfate and detec...

PURPOSE The expression of an array of signaling molecules, along with the assessment of real-time cell proliferation, has been performed in U87 glioma cell line and in patients' glioblastoma established cell cultures in order to provide a better understanding of cellular and molecular events involved in glioblastoma pathogenesis. Experimental therapy was performed using a phosphatidylinositol-3...

A chimpanzee (Pan troglodytes) experienced in counting arrays of 0-7 items and trained for comprehension of number symbols, spontaneously displayed a variety of indicating acts (e.g., pointing, touching, and rearranging items) during counting. Twenty-five sessions were videotaped, and all trials were evaluated for the relations among number of items presented, number of indicating acts displaye...