OBJECTIVE To determine if there was a difference in hard and soft tissue between northern Chinese and northern Indian adolescents with Angle Class II division 1 malocclusion. METHOD A total of 40 Angle Class II division 1 patients, including 20 boys and 20 girls aged 10 to 13 years with no prior treatment, were selected from northern China and northern India, respectively. Overall, 80 cephalo...

BACKGROUND & OBJECTIVES Cytogenetic microarray (CMA) is now recommended as a first-tier clinical diagnostic test in cases with idiopathic intellectual disability and/or developmental delay (ID/DD). Along with clinically relevant variants, CMA platforms also identify variants of unknown significance (VUS). This study was done to look for utility and various issues in interpretation of copy numbe...

The sickle cell gene in India represents a separate occurrence of the HbS mutations from those in Africa. Sickle cell disease in India occurs against different genetic and environmental backgrounds from those seen in African patients and there is evidence of clinical differences between the populations. Knowledge of the clinical features of African disease was drawn from the Jamaican Cohort Stu...