The binding energies of 121 complexes between anions and bis(cyclopeptides) differing in the structure number linking units two cyclopeptide rings were analyzed. These Gibbs free obtained earlier work for different anions, under conditions, with methods. multiparametric analysis a subset 42 afforded linear relationships that allowed relatively reliable estimation iodide sulfate affinity three s...

Abstract Bacterial type VI secretion systems (T6SSs) inject toxic effectors into adjacent eukaryotic and prokaryotic cells. It is generally thought that this process requires physical contact between the two Here, we provide evidence of contact-independent killing by a T6SS-secreted effector. We show pathogen Yersinia pseudotuberculosis uses T6SS (T6SS-3) to secrete nuclease effector kills othe...