We have synthesized a new and stable MR contrast agent, SPIO-mPEG-cRGD, that exhibits superior binding to the biologic target αvβ3 integrins. Selective targeting of αvβ3 integrins was achieved by conjugating cyclic RGD peptides to the superparamagnetic iron oxide nanoparticles (SPIO) surface, while poly(ethylene glycol) (PEG) were used for nonimmunogenic, nonantigenic and protein resistant. The...

Arguably nothing is more important to long-run improvement in human well being than a high quality basic education for every child and this has been enshrined as a development goal even before there were development goals. Promoting the achievement of this goal around the world requires a serviceable general positive model of education policies—a coherent causal explanation of why governments a...

The field of Classics is an inherently interdisciplinary one, combining within itself the disciplines of linguistics, history, literature, archaeology, and philosophy. In addition, Classics provision in the UK secondary school system is extremely uneven; while some students will have had eight or more years of instruction in the field prior to attending university, others might have none at all...

Writing instruction for engineering students involves differing perspectives and in some cases conflicting goals of many stakeholders including future employers, accrediting associations, writing center staff, and faculty in engineering, English, composition, and technical writing programs. These perspectives and conflicts can be addressed through a bottomup approach to WAC and WID: coursespeci...

The relationship between journalism and the academy is historically fraught. Any mention of the word ‘theory’ is only likely to exacerbate these tensions, since it perhaps signifies, most clearly, the division between both identities. Drawing on the social theory of Pierre Bourdieu, this paper considers, with particular empirical reference to the New Zealand context, the often antagonistic rela...

Background: the author describes shamans as practitioners who deliberately shift their phenomenological pattern of attention, perception, cognition, and awareness in order to obtain information not ordinarily available to members of the social group that granted them privileged status. Objectives: to describe how these phenomenological shifts were accomplished and used. Methods: archival studie...

This paper presents an overview of the development of current practice in information literacy education in tertiary institutions in South Africa. The policy framework affecting information literacy is examined from multiple perspectives. An examination of the literature identifies key concerns that are used in the compilation of a small survey instrument to establish current practice. The impa...

Studies of orthographic skills transfer between languages focus mostly on working memory (WM) ability in alphabetic first language (L1) speakers when learning another, often alphabetically congruent, language. We report two studies that, instead, explored the transferability of L1 orthographic processing skills in WM in logographic-L1 and alphabetic-L1 speakers. English-French bilingual and Eng...

Economic inequality is widely regarded as one of the most important issues our time. Extreme economic disparities destabilize democracy—as richest exert increasing control over political outcomes—and lead to forms social stratification which take a severe toll on mental wellbeing worst-off. also plays key role in driving ongoing ecological catastrophe, spending habits wealthiest tend be concent...

Mental health support workers (MHSWs) make positive contributions to mental recovery practice yet their roles and needs are often unclear. This research explored the occupational lived experiences of three MHSWs working in Irish healthcare services. The study examined perceptions regarding work. A narrative design was used incorporating participatory art-based inquiry as a collaborative means e...