OBJECTIVE To estimate the incidence of venous thromboembolism, acute myocardial infarction, and ischemic stroke among transdermal contraceptive system users compared with users of norgestimate-containing oral contraceptives with 35 mcg ethinyl estradiol. METHODS We began with insurance claims data from UnitedHealthcare. We identified women exposed to the transdermal contraceptive system or no...

In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration ...

background: epidemiologic aspects of oral and pharyngeal cancers in iran have not been studied adequately. we evaluated age-adjusted incidence rates by sex using pathological confirmed cases between 1991 and 2002 in kerman province, south east­ern iran. methods: the information of cases was collected actively from all of the 18 histopathology departments around the prov­ince. the standardize ri...

loess and loess-like deposits cover large areas of golestan province of iran, a well-known region in the world for its high incidence rate of esophageal cancer (ec). despite numerous published works on the possible contributing factors for the observed high incidence rate, very little attention has been given so far to a possible link between the mineralogy of loess deposits in the region and e...

This paper compares three different methods for performing cancer incidence prediction in an area without a cancer registry under a Bayesian framework, using linear and log-linear age-period models with either age-specific slopes or a common slope across age groups. The three methods assume that a nearby area with a cancer registration has similar incidence and mortality patterns as the area of...

Self-reported food frequency questionnaires (FFQs) have occasionally been used to investigate the association between whole-grain intake and the incidence of colorectal cancer, but the results from those studies have been inconsistent. We investigated this association using intakes of whole grains and whole-grain products measured via FFQs and plasma alkylresorcinol concentrations, a biomarker ...

The incidence of major amputations following gangrene of the lower limb during the period 1971 to 1979 in the county of Copenhagen was calculated. The overall incidence was found to be about 0.3 per thousand inhabitants over 40 years of age, the ratio of men to women was 2:1. The incidence was found to increase exponentially with age. The amputation-rate of the lower limb did not change during ...

OBJECTIVE To determine whether the daily risk of central line-associated bloodstream infections (CLABSIs) increases over the dwell time of peripherally inserted central catheters (PICCs) in high-risk neonates. METHODS Multicenter retrospective cohort including NICU patients with a PICC inserted between January 2005 and June 2010. We calculated incidence rates and used Poisson regression model...