نتایج جستجو برای: inactivated probiotics
تعداد نتایج: 31516 فیلتر نتایج به سال:
Probiotics are identified as “Live microorganisms which when administered in adequate amounts confer a health benefit on the host” [1]. Although different microorganisms are claimed today as probiotics, usually they represent two main genera Lactobacillus and Bifidobacterium. Other probiotic bacteria have received limited attention of researchers. Among them are Bacillus bacteria highly diverse...
Probiotics are increasingly used for prevention and treatment of diarrhea more in children than in adults. Given the broad spectrum of diarrhea, this review focuses on the main etiologies: acute gastroenteritis, antibiotic-associated diarrhea (AAD), and necrotizing enterocolitis (NEC). For each, we reviewed randomized controlled trials, meta-analyses, and guidelines. For acute gastroenteritis w...
BACKGROUND Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% and reaches 20-30% in those with an allergic first-degree relative. Intestinal microbiota may modulate immunologic and inflammatory systemic responses and, thus, influence development of sensitization and allergy. Probiotics have been reported to modulate immune responses ...
Previous clinical studies have reported mixed results regarding the effect of probiotics on lipid metabolism. Therefore, we conducted a meta-analysis of randomized controlled trials to quantify the direction and magnitude of the potential effect of probiotics on blood lipid concentrations.Eligible studies were randomized, placebo-controlled trials whose interventions were probiotic products con...
BACKGROUND/AIMS Dysfunction of autophagy has been associated with loss of intestinal homeostasis. Lipopolysaccharide (LPS) from Gram-negative bacteria is known to be a major initiator of intestinal epithelial cell (IEC) autophagy. Although probiotics have been recognized to be involved in many therapeutic properties and participate in host defense responses, the molecular mechanisms by which pr...
Probiotics are live commensal microorganisms of the intestinal tract that confer multiple gastro-intestinal health benefits to the host. Yet, the exact mechanisms by which probiotics ameliorate experimental colitis in animals and human inflammatory bowel disease are largely unknown. We tested whether the attenuation of experimental colitis by live probiotic bacteria is mediated by Toll-like rec...
Orally administered probiotics change gut microbiota composition and enzyme activities. Thus, coadministration of probiotics with drugs may lead to changes in the pharmacokinetic parameters of the drugs. In this study, we investigated the pharmacokinetics of acetaminophen in mice treated with probiotics. Oral administration of probiotics changed the gut microbiota composition in the mice. Of th...
OBJECTIVE To review the effects of probiotics and prebiotics in clinical pediatric practice. SOURCES MEDLINE was searched, especially for articles that addressed their practical application, in the form of reviews, clinical trials and meta-analyses. Articles that had already been analyzed by the authors were also included. SUMMARY OF THE FINDINGS Scientific literature on probiotics and preb...
PURPOSE OF REVIEW Few therapies are of proven efficacy in irritable bowel syndrome. Thus, there is great interest in the development of a natural therapy that can be both safe and effective. An understanding that probiotics are heterogeneous, with multiple targets and mechanisms of action, is fundamental to the development of clinical trials. RECENT FINDINGS A bidirectional model for the path...
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