نتایج جستجو برای: in vitro release studies
تعداد نتایج: 17166397 فیلتر نتایج به سال:
The objective of the present study was to prepare controlled release formulation of Moxifloxacin hydrochloride ocular nanoparticles. The nanoparticles were prepared by solvent displacement method using Eudragit RL 100 as a polymer. Different formulations were prepared by varying the ratios of drug and polymer and varying the ratios of organic and aqueous phase. The formulations were evaluated i...
the aim of this investigation was to design and develop nanoemulsions (nes) as novel ophthalmic delivery systems for brinzolamide (bzd). phase behavior of quaternary systems composed of triacetin and capryoltm 90 (selected oils, screened through the solubility studies), various surfactants (namely, cremophor rh 40, brij 35, labrasol and tyloxapol), transcutol p (as co-surfactant) and water a...
Studies on Mefenamic Acid Microparticles: Formulation, In Vitro Release, and In Situ Studies in Rats
objective(s): the quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. aim of this study is to find out the isoniazid release kinetic. methods: in this work degradable temperature sensitive dextran-hydroxy ethyl methacrylate- poly-n-isopropyl acryl amide (dex-hema-pnipaam) nan...
The present investigation was aimed at developing a novel colon targeted system of lornoxicam based on the use of a combination of pH dependent system (to prevent the premature release of drug in the upper GIT) and enzymatically degradation system (to ensure the specificity of drug release in the colon). The drug loaded guar gum microspheres prepared by emulsification cross-linking method were ...
A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...
Introduction: Anal fissures are small tears in the lining skin of the anus presenting with typical symptoms of pain and bleeding during defecation. Several new forms of medicines such as glyceryle trinitrate (GTN) ointments and diltiazem, a calcium channel-blocking agent, have been recently used for the treatment of these fissures. Diltiazem relaxes the muscle of anal sphincter and consequently...
چکیده در دنیای پیچیده ی امروز، تغییرات زیادی در زندگی بشری در حال وقوع اند و شاهد رقابت های بسیار فشرده ی جوامع در دستیابی به فناوری برتر و قدرت بیشترهستیم. به نظر می رسد که فرد وجامعه مجبورند به طریقی در وضعیت خویش دگرگونی ایجاد کنند تا از قافله ی علم، فناوری، و پیشرفت عقب نمانند. رشته مطالعات ترجمه نیز از این قاعده مستثنا نیست. علی رغم وسعت روز افزون پژوهش در این حوزه و میان رشته ای بودن مطال...
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