background: therapeutic potential of in vitro maturation (ivm) in infertility is growing with great promise. although significant progress is obtained in recent years, existing ivm protocols are far from favorable results. the first aim of this study was to investigate whether two step ivm manner change reactive oxygen species (ros) and total antioxidant capacity (tac) levels. the second aim wa...

introduction: dehp [di(2-ethylhexyl) phthalate)] is widely used in plastic industry and some reproductive toxicity has been shown with it. so, this study was designed to evaluate dehp effects on resumption of meiosis and in vitro maturation of mouse oocytes as well as development of embryos resulted from them. material and methods: mice of 4-6 weeks old were administered daily doses of 50, 100,...

objective: currently, there is no agreement on the optimal urinary derived human chorionic gonadotropin (u-hcg) dose requirement for initiating final oocyte maturation prior to oocyte collection in in vitro fertilization (ivf), but doses that range from 2500- 15000 iu have been used. we intended to determine whether low dose u-hcg was effective for oocyte maturation in ivf/intracytoplasmic sper...

Background: Cryobiology and in vitro maturation of oocytes are very important tools of reproductive technology. Oocyte plays an important role in fertility. The objective of this research is comparison study the effect of invitro maturation and IVF fertilization of cryopreserved oocyte with fresh oocyte in mice. Materials and Methods: For this purpose, after superovulation was performed oocytes...

conclusions the present study showed that vitrification using cryotop and freezing medium can damage oocytes by reducing the maturation and fertilization rates in both developmental stages. results vitrification caused a significant reduction in the maturation rate of oocytes. of those that matured, the fertilization rate of vitrified ivm-mii (44.1%) and ov-mii oocytes (50%) was not significant...

Since the pioneering days of in vitro fertilization, hCG has been the gold standard to induce final follicular maturation. We herein reviewed different pharmaceutical options for triggering of final oocyte maturation in ART. The new upcoming agent seems to be GnRHa with its potential advantages over hCG trigger. GnRHa triggering elicits a surge of gonadotropins resembling the natural midcycle s...

some cases of male infertility are due to the destructive side-effects of anticancer treatment methods such as chemo and radiotherapies on germ cell lines. the increase in the survival rate of cancer patients who undergo treatment, especially children, has drawn attention to fertility preservation. the most common and effective technique in preserving male fertility is sperm freezing and its su...