The incidence of exfoliative toxin-producing strains of Staphylococcus aureus was studied. Samples from hospitalized patients of all ages and samples from infants less than 6 weeks old were screened; out of 2,632 coagulase-positive S. aureus strains tested, 6.2% synthesized exfoliative toxin. The clinical features could be assessed in 86 patients harboring exfoliative toxin-producing staphyloco...

The pharmacokinetics of cefadroxil suspension were studied in 30 children, 13 months to 12 years of age (mean age, 5.7 years). Average peak concentrations in serum of 11 to 14 mug/ml and of 7 to 10 mug/ml after 15- and 10-mg/kg doses, respectively, were not substantially affected by the feeding status. The serum half-life values were 1.3 to 1.5 h. Cefadroxil was detected in saliva of all childr...

Since 2006 in Denmark, there has been a statutory order on physicians' notification of methicillin-resistant Staphylococcus aureus (MRSA). Occupational cases notified in North Denmark Region in 2008 and 2009 were analysed. Overall, 109 cases (54 females and 55 males) were notified, of whom 56 were infected and 52 cases were carriers, whereas in one case the status was unknown. The most prevalen...

OBJECTIVES To describe the problems faced by children during separation from their imprisoned mothers, and evaluate the health of children who accompanied their mothers into prison. DESIGN A prospective observational study. SETTING Welikada Prison, Colombo, Sri Lanka. METHODS 200 randomly selected mothers who had left their children at home were interviewed using a questionnaire. During a...

In the last few years, serious cases of group A streptococcus (GAS) invasive infections have been increasing worldwide. Many questions related to this entity remain unanswered, especially those of secondary cases in close contact with an index patient. Household clusters have been described but are not numerous, and no study has yet clearly established the risk of acquiring the infection in thi...