We present a label-free biosensor based on electrochemical impedance spectroscopy for the detection of proinflammatory cytokine Tumor Necrosis Factor (TNF-α). Secretion of TNF-α has been correlated to the onset of various diseases including rheumatoid arthritis, Crohn’s disease etc. Gold electrodes were patterned on a silicon substrate and self assembled monolayer of dithiobis-succinimidyl prop...

Local Electrochemical Impedance Spectroscopy (LEIS) is an emerging discipline in the field of electrochemical research. It is based on the widely accepted Electrochemical Impedance Spectroscopy (EIS) technique, a powerful method to determine reaction mechanisms on macroscopic electrodes. When however the electrode represents a heterogeneous behavior, local information is indispensable. This pro...

Carbon nanotubes have been explored as interconnects in solid acid fuel cells to improve the link between nanoscale Pt catalyst particles and macroscale current collectors. The nanotubes were grown by chemical vapor deposition on carbon paper substrates, using nickel nanoparticles as the catalyst, and were characterized using scanning electron microscopy and Raman spectroscopy. The composite el...

The interactions of recombinant juvenile hormone binding protein (His8-rJHBP) with juvenile hormones (JHs), methoprene and farnesol have been studied with electrochemical impedance spectroscopy (EIS). The protein was immobilized on the dodecanethiol (DDT) modified gold electrodes. Each step of electrode modification has been confirmed with cyclic voltammetry (CV) and electrochemical impedance s...

A maximum length sequence (MLS) is used to perform broadband impedance spectroscopy on a dielectric sample. The method has a number of advantages over other pulse-based or frequency sweep techniques. It requires the application of a very short sequence of voltage steps in the microsecond range and therefore allows the measurement of time-dependent impedance of a sample with high temporal resolu...

Development of appropriate models for the interpretation of impedance spectra in terms of physical properties requires, in addition to insight into the chemistry and physics of the system, an understanding of the measurement error structure. The time-varying character of electrochemical systems has prevented experimental determination of the stochastic contribution to the error structure. A met...

The interaction of DNA with quercetin was studied using scanning electrochemical microscopy and electrochemical impedance spectroscopy at glass carbon electrode. Information such as the surface coverage of the film and apparent rate constant of the redox active probe in solution was obtained. It is deduced that quercetin interacting with DNA forms a kind of electrochemical inactive supramolecul...

Corrosion inhibition of mild steel in 1 M HCl and 0.5 M H2SO4 by dapsone were studied by polarization resistance, Tafel polarization, electrochemical impedance spectroscopy (EIS) and weight loss measurement. Results obtained revealed that inhibition occurs through adsorption of the drug on metal surface without modifying the mechanism of corrosion process. Potentiodynamic polarization suggested...

Solution-based organic field-effect transistors (OFETs) with low parasitic capacitance have been fabricated using a self-aligned method. The self-aligned processes using a cross-linking polymer gate insulator allow fabricating electrically stable polymer OFETs with small overlap area between the source-drain electrodes and the gate electrode, whose frequency characteristics have been investigat...