نتایج جستجو برای: immunosuppressive drug
تعداد نتایج: 607565 فیلتر نتایج به سال:
Despite advances in understanding autoimmune diabetes in animal models, there has been little progress in altering the natural course of the human disease, which involves progression to insulin deficiency. Studies with immunosuppressive agents have shown short-term effectiveness, but they have not induced tolerance, and continuous treatment is needed. We studied the effects of hOKT3gamma1(Ala-A...
The innervation of teeth mediated by axons originating from the trigeminal ganglia is essential for their function and protection. Immunosuppressive therapy using Cyclosporine A (CsA) was found to accelerate the innervation of transplanted tissues and particularly that of bioengineered teeth. To avoid the CsA side effects, we report in this study the preparation of CsA loaded poly(lactic-co-gly...
The present study aimed to evaluate the effects of an individualized, low-dose multi-drug immunosuppressive regimen for the treatment of immunoglobulin A nephropathy (IgAN). A preliminary investigation of the course of IgAN following immunosuppressive treatment was conducted based on repeat renal biopsies. Clinical and pathological data of 17 patients with IgAN who received repeat renal biopsie...
pneumocystis jirovecii causes pneumocystis pneumonia (pcp) in immunocompromised patients with a high rate of morbidity and mortality. colonization with this fungus may stimulate pulmonary inflammation or lead to pcp in susceptible patients. the epidemiology of this infection and routs of its transmission has poorly studied in iran. we examined pneumosystis colonization in patients with various ...
Invasive fungal infections cause significant morbidity and mortality in patients with concomitant underlying immunosuppressive diseases. The recent addition of new triazoles to the antifungal armamentarium has allowed for extended-spectrum activity and flexibility of administration. Over the years, clinical use has raised concerns about the degree of drug exposure following standard approved dr...
For most drugs, initial dosage for different individuals is associated with many factors, such as weight and age. If drug blood concentrations can be measured, the dosage of the drug may be adjusted to the blood value to get an acceptable range. With regards to immunosuppressive drugs, like tacrolimus, dose that is too low could cause organ rejection, and a dose that is too high could cause tox...
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