Diffuse large B-cell lymphoma (DLBCL) of the heart accounts for only 1% primary cardiac tumors. Histopathologic examination becomes key diagnosis and immunohistochemical evaluation non-Hodgkin (NHL) subtype determination is able to predict disease progression therapeutical modality. Case description: 70-year-old man complained shortness breath. Echocardiographic revealed mass occupied left atri...

Abstract PURPOSE This study aimed to investigate the methylation status of major histone modification sites in PCNSL samples and examine their prognostic role patients. METHODS Between 2007 2020, 87 patients were histopathologically diagnosed as PCNSL, they treated with same protocol high-dose methotrexate-based combination chemotherapy. Clinical data for PFS OS was obtained from medical record...

background and objective: inflammatory pseudotumor  is a lesion composed of proliferating spindle cells with mixed inflammatory infiltrates. some authors have proposed the name inflammatory myofibroblastic tumor as a proper descriptive term rather than the vague inflammatory pseudotumor. the aim of this study was to verify the myofibroblastic origin of spindle cells in idiopathic orbital inflam...

the transcriptional factor oct4 regulates pluripotency of stem cells and has an important role during oocyte growth. whereas, its role has remained ambiguous in ovarian tissue during reproductive cycle. therefore, this study was aimed to investigate the expression patterns of oct4 in mouse ovaries during the normal estrous cycle. adult national medical research institute mice were classified as...

We evaluated the usefulness of double immunohistochemical staining for cytokeratin (CK)5/6 and alpha-methylacyl coenzyme A racemase (AMACR) applied sequentially on 1 slide by assessing 223 foci in 110 consecutive prostate specimens. Double-chromogen reaction was used to visualize the antibodies: brown for CK5/6 and red for AMACR. Staining was scored as diffuse, focal, or negative. To establish ...

Abstract Background Osteoarthritis (OA) is a chronic degenerative disease that suppresses middle-aged and older people worldwide. Silent information regulator 1(SIRT-1) associated with several age-related diseases, such as cardiovascular neurodegenerative diseases tumors, etc. The protective role of SIRT-1 in bone joint has become increasingly well known. Objective To explore the relationship b...

A 46-year-old woman with epigastric pain was found to have a cystic tumor in the pancreas head on radiological examinations. The tumor was hypervascular, and its multilocular appearance resembled the "honeycomb" pattern of serous cystic tumor (SCT). The patient underwent surgery. The cut surface of the tumor showed a thick fibrous capsule with multiple cystic components, which contained necroti...

BACKGROUND/AIMS Although the standard treatment for desmoid tumours is complete surgical resection with wide margins, the optimal adjuvant treatment for recurrent or inoperable disease is unclear, often being based on sporadic immunohistochemical reports with a low number of cases. Therefore, a large immunohistochemical study was performed, to provide a theoretical basis for adjuvant treatment ...

OBJECTIVES Carcinoembryonic antigen (CEA) is widely used for postoperative surveillance of colon cancer. Even if serum CEA is negative at initial surgery, it may turn positive at recurrence. We investigated the relation between serum CEA levels and the immunohistochemical staining status of CEA in the primary and resected metastatic tissues. METHODS Out of 224 patients with recurrent colon ca...