abstract introduction: thalassemia is the most common hereditary anemia in iran. the aim of this study was to evaluate the humoral immune system and assess the effect of splenectomy on the serum level of immunoglobulins igg, igm, and iga and complement components in patients with major thalassemia. materials and methods: this interventional semi-experimental study (before-after) was performed o...

Immunoglobulin, which is also called an antibody, a type of serum protein produced by B cells that can specifically bind to the corresponding antigen. Immunoglobulin closely related many diseases and plays key role in medical biological circles. Therefore, use effective methods improve accuracy immunoglobulin classification great significance for disease research. In this paper, CC–PSSM monoTri...