HIV-positive as well as other immunocompromised women and men have increased risk of human papillomavirus (HPV)-associated nogenital and oral cancers. The effectiveness of a HPV vaccine to reduce the incidence of these tumors in immunocompromised individuals ay depend on several factors, including the effects of immunocompromise on the response to vaccination, the extent of prior infection ith ...

Immunocompromised patients are usually seriously ill and many such patients, especially those undergoing stem cell transplantation, have prolonged periods of pancytopenia and consequently, heavy transfusion requirements. All transfusions are potentially hazardous but transfusions to immunocompromised patients cause additional problems, which may be immunological or infectious. This review descr...

The number of granulocytes is maintained by a regulated balance between granulopoiesis in the bone marrow and clearance and destruction in peripheral tissues. Granulopoiesis plays a fundamental role in the innate immune response. Therefore, factors affecting the normal granulopoiesis lead to alterations in innate defenses and reduce the resistance against infections. In this study, we give a de...

Copyright © 2012 Massachusetts Medical Society. Infectious gastroenteritis is a common, acute illness that is characteristically self-limiting, but it can become debilitating and life-threatening in immunocompromised patients.1 Noroviruses are major pathogens among the microbes associated with gastroenteritis in both immunocompetent and immunocompromised hosts1-4 (Table 1). In the United States...

Immune Deficiency Foundation, the national nonprofit organization devoted to research and education for the primary immune deficiency diseases, publishes other materials for physicians and healthcare professionals (eg. Physician’s Primer and Guide for Nurses) and for patients (eg.Patient and Family Handbook, Our Immune System, and Newsletter). For Information about our programs, patient groups ...