Complementary idiotypes or antibodies are considered to have combining site structures which are at least partly directed against each other. Complementary antibodies were induced in A/He mice by immunization with phosphorylcholine (PC)-containing antigens and by immunization with the PC-binding IgA myeloma protein TEPC-15 (T15). Both responses were monitored by enumerating plaque-forming cells...

BACKGROUND Between 1999 and 2002, a multistate demonstration project was conducted in long-term care facilities (LTCFs) to encourage implementation of standing orders programs (SOP) as evidence-based vaccine delivery strategies to increase influenza and pneumococcal vaccination coverage in LTCFs. OBJECTIVE Examine predictors of increase in influenza and pneumococcal vaccination coverage in LT...

The COVID-19 pandemic caused many effects on the referrals to and work of governmental agencies working with young children. This article describes impact use early childhood evaluations services in State Hawaii. We looked at several nonpublic data sets from Hawaii Department Health Human Services, comparing rates intervention referrals, lead level screening, immunizations, child welfare 2019 2...

tronic systems must talk with each other or the whole process falls apart. the Wisconsin Pharmacy Quality collaborative is a program of the Pharmacy Society of Wisconsin that received an innovation award from centers for Medicare & Medicaid Services to improve medication management for the people of Wisconsin. the special article in this issue of the WMJ describes the project and its goals and ...

BACKGROUND Barriers to adult immunizations persist as current rates for pneumococcal polysaccharide vaccine (PPV) receipt among eligible adults remain below national goals. This study investigated potential barriers to patients receiving the PPV, including predisposing, enabling, environmental and reinforcing factors among physicians from a variety of practice and geographic settings. METHODS...

The clinical and immunological effects of a vaccine consisting of CTP37, a synthetic peptide corresponding to the COOH-terminal peptide (CTP) of beta-human chorionic gonadotropin (beta-hCG) conjugated to diphtheria toxoid, combined with CRL 1005, a novel synthetic nonionic block copolymer adjuvant, were examined. Twenty-one patients with metastatic, nontrophoblastic cancers received up to four ...

OBJECTIVE To explore the experiences of family physicians and pediatricians delivering immunizations, including perceived barriers and supports. DESIGN Qualitative study using focus groups. SETTING Ten cities throughout British Columbia. PARTICIPANTS A total of 46 family physicians or general practitioners, 10 pediatricians, and 2 residents. METHODS A semistructured dialogue guide was u...

Not much is known about how health insurance affects preventive care for children who have access to general routine paediatric care, especially in less developed settings. This study evaluates the effects of child health insurance on preventive care (measured by whether the child had received all the age-appropriate immunizations) for children with access to routine paediatric care. It uses a ...