In any one strain the occurrence of the previously recognized type-specific protein, M, is usually completely correlated with the presence of the recently recognized type-specific antigen, T. Strain C203 is exceptional in having the T substance of type 1 as well as the two type-specific antigens, M and T, characteristic of type 3. It does not have the M antigen of type 1. While other strains wi...

The phenomenon of conglutination was first reported by Ehrlich and Sachs (1902), and subsequently received attention from Bordet and Gay (1906) and Bordet and Streng (1909). However, a systematic study of the mechanisms involved did not appear until Coombs and associates, in a commendable series of papers, reviewed the earlier work (Hole and Coombs, 1947a), applied the test to certain virus sys...

A brief explanation of cellular and humoral immunity. Although immunity involves every orvm and system of the body, the typical conceptualization of the immune system consists of lymphocytes divided into two major divisions: the humoral mid cellular aspects. Humoral immunity includes primarily B lymphocytes and has to do with antigen/antibody reactions. These are the reactions involved in type ...

Earthworms are able to protect themselves against invading microorganisms through their immune systems. Although there are many studies about defense systems of Dendrobaena veneta, this is the first report focusing on the immune properties of earthworms belonging to the same species, which live in different localities. Thus, it was aimed to compare antibacterial and hemolytic activities of eart...

Awareness that advancing cancer is often accompanied by defective imnmnologic responses, and accumulating evidence that immune reactions may influenee the course of cancer, has stimulated the study of various meehanisms of immunologic reaction in patients with cancer. As part of such a program we have determined the serum level of the second component of complement in a group of cancer patients...

Antibodies to antigens in the Kell blood group system are usually immunoglobulin G, and, notoriously, anti-K, anti-k, and anti-Kp(a) can cause severe hemolytic transfusion reactions, as well as severe hemolytic disease of the fetus and newborn (HDFN). It has been shown that the titer of anti-K does not correlate with the severity of HDFN because, in addition to immune destruction of red blood c...

It is shown that when dilute rabbit serum rich in agglutinin for the hog cholera bacillus is heated at 75 degrees C. for 20 minutes and the bacilli incubated with the heated serum, agglutination fails to result on the addition of unheated immune serum. When the immune serum is first heated to 80 degrees C., it no longer greatly inhibits secondary agglutination when the organisms are exposed to ...

OBJECTIVE To review and summarize the body of literature regarding human intravenous immunoglobulin (hIVIG) therapy in veterinary medicine. Mechanism of action, usage in human medicine, adverse effects of therapy, implications for veterinary use, and administration recommendations are discussed. DATA SOURCES Current human and veterinary peer-reviewed medical literature including original rese...