Several factors limit the efficacy of nematicides. Consequently, modifications can be made to their active ingredient, formulation, and application to increase their efficacy.

Objective: In this review, we aimed to discuss the efficacy of immunotherapy anti-programmed cell death protein 1 (PD-1) and programmed ligand (PD-L1) potential immune mechanism combination with various standard systemic therapies for breast cancer (BC) such as chemotherapy, targeted therapy, endocrine radiotherapy.

This paper explores the introduction of a screening test to highlight impaired immune system status for newborn infants and its efficacy as a preventative clinical measure. Moreover, it is suggested that screening of the infantile immune system has the potential to highlight susceptibility to a range of infant and childhood diseases, bestowing an opportunity to introduce early intervention to r...

Since the approval of anti-CTLA4 therapy (ipilimumab) for late-stage melanoma in 2011, the development of anticancer immunotherapy agents has thrived. The success of many immune-checkpoint inhibitors has drastically changed the landscape of cancer treatment. For some types of cancer, monotherapy for targeting immune checkpoint pathways has proven more effective than traditional therapies, and c...

The purpose of the present study was to apply Berg and Upchurch's (2007) developmental-conceptual model to understand better how couples cope with cancer. Specifically, we hypothesized a dyadic appraisal model in which proximal factors (relational quality), dyadic appraisal (prognosis uncertainty), and dyadic coping (communication efficacy) predicted adjustment (cancer management). The study wa...

The study was designed to estimate the psychometric properties of Hastings and Brown's (2002a) Difficult Behavior Self-efficacy Scale. Participants were two samples of physical educators teaching in Korea (n=229) and the United States (U.S.; n=139). An initial translation of the questionnaire to Korean and pilot study were conducted along with the larger study using a confirmatory factor analys...

Cancer dormancy, a state in which cancer cells persist in a host without significant growth, is a natural forestallment of progression to manifest disease and is thus of great clinical interest. Experimental work in mice suggests that in immune-induced dormancy, the longer a cancer remains dormant in a host, the more resistant the cancer cells become to cytotoxic T-cell-mediated killing. In thi...

artificial immune systems (ais) can be defined as soft computing systems inspired by immune system of vertebrates. immune system is an adaptive pattern recognition system. ais have been used in pattern recognition, machine learning, optimization and clustering. feature reduction refers to the problem of selecting those input features that are most predictive of a given outcome; a problem encoun...

Immune checkpoint inhibitors (ICIs) are designed to reinvigorate antitumor immune responses by interrupting inhibitory signaling pathways and promote the immune-mediated elimination of malignant cells. Although ICI therapy has transformed landscape cancer treatment, only a subset patients achieve complete response. Focused ultrasound (FUS) is noninvasive, nonionizing, deep penetrating focal tha...