Background: Nowadays, the immune response to hepatitis C (HCV) treatment has become a crucial issue mostly due to the interleukin 28B (IL-28B) polymorphism effects in chronic HCV patients. The aim of this study was to detect the polymorphism of IL-28B gene (rs12979860) in HCV genotype 1 patients treated with pegylated Interferon and Ribavirin. Methods...

Background: IL-10 is an anti-inflammatory cytokine which is involved in tumorigenesis. Over production of IL-10 and elevated number of IL-10 generating mononuclear cells in breast tumor tissue has already been shown. Objective: To determine the association of IL-10 promoter polymorphisms with increased risk of breast cancer and its association with breast cancer prognostic factors. Methods: Per...

Recent studies report that individuals with polymorphisms in the genes encode for interleukin (IL)-1α and IL-1β (IL-1A IL1B, respectively) IL-1 receptor antagonist (IL-1RN) may be more susceptible developing peri-implantitis. Therefore, current systematic review evaluates what is reported about role of genetics, specifically single nucleotide (SNP) on variable number tandem repeats (VNTR) IL-1R...

The purpose of this paper is to prove various independence of ` results for correspondences acting on the étale cohomology of algebraic varieties in positive characteristic. The most basic result in this direction is the following: Theorem 1.1 (special case of 7.12). Let k be an algebraically closed field, and let X/k be a separated scheme of finite type. Let u : X → X be a quasi-finite morphis...

We describe a general method for modelling γ -ray burst (GRB) prompt emission, and determine the range of magnetic field strength, electron energy, Lorentz factor of the source and the distance of the source from the central explosion that is needed to account for the prompt γ -ray emission of a typical long-duration burst. We find that for the burst to be produced via the synchrotron process u...

This review aimed to describe the interleukins and interleukin gene polymorphisms related recommended as a RAS biomarker. Articles were searched through PubMed, ScienceDirect, Cochrane Library databases, using keywords of “Interleukin” AND “Recurrent Aphthous Stomatitis”. The Risk Bias Assessment tool for Non-randomized Studies (RoBANS) was used, writing this refers Preferred Reporting Items Sy...

Background: Pre-eclampsia (PE) is known as a main factor contributing to fetomaternal mortality, which might affect 2-8% of all pregnancies after the twentieth week of gestation. The balance of T helper subsets is essential to sustain a normal pregnancy and preventing fetomaternal complications. Objective: To investigate differences in the levels of transcription factors and cytokine gene e...